1369351-96-1Relevant articles and documents
Perturbing pro-survival proteins using quinoxaline derivatives: A structure-activity relationship study
Rajule, Rajkumar,Bryant, Vashti C.,Lopez, Hernando,Luo, Xu,Natarajan, Amarnath
, p. 2227 - 2234 (2012)
In HeLa cells the combinatorial knockdown of Bcl-xL and Mcl-1 is sufficient to induce spontaneous apoptosis. Quinoxaline derivatives were screened for the induction of Mcl-1 dependent apoptosis using a cell line without functional Bcl-xL. Quinoxaline urea