1369558-93-9

Basic information

• Product Name: 3‐((3‐methoxyphenyl)thio)‐2‐phenyl‐1H‐indole
• Synonyms: 3‐((3‐methoxyphenyl)thio)‐2‐phenyl‐1H‐indole
• CAS NO: 1369558-93-9
• Molecular Weight: 331.438
• Mol File: 1369558-93-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3‐((3‐methoxyphenyl)thio)‐2‐phenyl‐1H‐indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3‐((3‐methoxyphenyl)thio)‐2‐phenyl‐1H‐indole(1369558-93-9)
• EPA Substance Registry System: 3‐((3‐methoxyphenyl)thio)‐2‐phenyl‐1H‐indole(1369558-93-9)

Safety Data

• Hazardous Substances Data: 1369558-93-9(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 15570-12-4 3-methoxybenzenethiol 
• 199277-23-1 1-azido-2-(phenylethynyl)benzene 
• 948-65-2 2-phenyl-indole 
• 1561023-51-5 sodium S-(3-methoxyphenyl) thiosulfate 
• 59014-89-0 bis(3-methoxyphenyl)disulfide 

Relevant articles and documents

Synthesis of 3-Sulfenylindoles from Indoles and Various Sulfenylation Agents through Aerobic Oxidative C-S Bond Coupling

A novel aerobic catalytic oxidation system for the sulfenylation of indoles with a variety of sulfenylation agents through oxidative C-S bond coupling has been successfully developed. The reactions were performed with potassium iodide as the catalyst, sodium nitrite as the co-catalyst, and molecular oxygen as the terminal oxidant in the presence of acetic acid. Under the optimal reaction conditions, a number of indoles could be sulfenylated with Bunte salts, thiols, or disulfides to generate 3-sulfenylindoles in good yields. This protocol provided an efficient and environmentally benign strategy for the synthesis of 3-sulfenylindoles.

Nitrosonium ion catalysis: aerobic, metal-free cross-dehydrogenative carbon-heteroatom bond formation

Catalytic cross-dehydrogenative coupling of heteroarenes with thiophenols and phenothiazines has been developed under mild and environmentally benign reaction conditions. For the first time, NOx+ was applied for catalytic C-S and C-N bond formation. A comprehensive scope for the C-H/S-H and C-H/N-H cross-dehydrogenative coupling was demonstrated with >60 examples. The sustainable cross-coupling conditions utilize ambient oxygen as the terminal oxidant, while water is the sole by-product.

Catalytic Synthesis of 3-Thioindoles Using Bunte Salts as Sulfur Sources under Metal-Free Conditions

An efficient catalytic method for the synthesis of 3-thioindoles has been successfully developed, which uses odorless, stable, readily available crystalline Bunte salts as the sulfenylating agents, iodine as nonmetallic catalyst, and DMSO as both the oxid