137022-35-6

Basic information

• Product Name: Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-
• Synonyms: 1-((2R,4S,5S)-4-Amino-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-benzyloxymethyl-1H-pyrimidine-2,4-dione
• CAS NO: 137022-35-6
• Molecular Formula: C17H21N3O5
• Molecular Weight: 347.36600
• Mol File: 137022-35-6.mol
• Article Data: 1

Chemical Properties

• Density: 1.325±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-(137022-35-6)
• EPA Substance Registry System: Thymidine, 3'-amino-3'-deoxy-a-(phenylmethoxy)-(137022-35-6)

Safety Data

• Hazardous Substances Data: 137022-35-6(Hazardous Substances Data)

Upstream product

• 98808-20-9 O,O'-bis(trimethylsilyl)-5-benzyloxymethyluracil 
• 123212-51-1 1,5-Di-O-acetyl-2,3-dideoxy-3-phthalimido-β-D-erythro-pentofuranose 
• 139703-08-5 1-(5'-O-acetyl-3'-phthalimido-2',3'-dideoxy-β-D-erythropentafuranosyl)-5-benzyloxymethyluracil 

Relevant articles and documents

Synthesis of 5-alkoxymethyl derivatives of 3'-amino-2',3'-dideoxyuridine and evaluation of their activity against HIV and cancer.

5-Alkoxymethyluracils 2a-c have been prepared by acid-catalyzed etherification of 5-hydroxymethyluracil (1). Compounds 1, 2a-c, 5-methoxymethyl- and 5-benzyloxymethyl-uracil were silylated and coupled with 1,5-di-O-acetyl-3-phthalimido-2,3-dideoxy-beta- D