1370351-45-3

Basic information

• Product Name: 4,4'-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4-diyl)dimorpholine
• CAS NO: 1370351-45-3
• Molecular Weight: 376.264
• Mol File: 1370351-45-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,4'-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4-diyl)dimorpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4-diyl)dimorpholine(1370351-45-3)
• EPA Substance Registry System: 4,4'-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4-diyl)dimorpholine(1370351-45-3)

Safety Data

• Hazardous Substances Data: 1370351-45-3(Hazardous Substances Data)

Upstream product

• 10244-24-3 2,4-[bis(morpholino)]-6-chloropyrimidine 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1312445-63-8 5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-trifluoromethylpyridin-2-ylamine hydrochloride 

Relevant articles and documents

And circular PI3K inhibitors (by machine translation)

The invention belongs to the field of medical technology, in particular to general formula (I) and of the everted shown in the PI3K inhibitor, or a pharmaceutically acceptable salt, ester, stereo isomers, solvates, wherein R 1, R 2, R 3 as defined in the specification. The invention also relates to methods of preparing such compounds, pharmaceutical formulations containing these compounds and pharmaceutical compositions, use of these compounds in the preparation and treatment and/or prevention of proliferative diseases of application of the medicament. (by machine translation)

MANUFACTURING PROCESS FOR PYRIMIDINE DERIVATIVES

The invention relates to processes for manufacturing a compound of formula (5) or a stereoisomer, tautomer or a salt thereof, wherein the substituents are as defined in the specification. The invention further relates to new manufacturing processes for specific solid forms of Compound A and its salts, to such solid forms and to use of said solid forms for the therapeutic treatment of warm-blooded animals.