137100-79-9Relevant articles and documents
Synthesis of thymidine from 5-iodo-2'-deoxyuridine
Herdewijn,Kerremans,Wigerinck,Vandendriessche,Van Aerschot
, p. 4397 - 4400 (2007/10/02)
A simple, high yield synthesis of thymidine from 5-iodo-2'-deoxyuridine is described, using tetramethyltin and tetrakis(triphenylphosphine)palladium(0) in hexamethylphosphoric triamide. Likewise, 5-phenyl- and 5-vinyl-2'-deoxyuridine can be obtained, and through reduction of the latter the 5-ethyl analogue is also at hand.