137104-42-8Relevant articles and documents
Design, synthesis and evaluation of 3-arylidene azetidin-2-ones as potential antifungal agents against Alternaria solani Sorauer
Delong, Wang,Yongling, Wu,Lanying, Wang,Juntao, Feng,Xing, Zhang
, p. 6661 - 6673 (2017/11/17)
A new concise and facile method was explored to synthesize a collection of new 3-arylidene azetidin-2-ones, which could be regarded as the derivatives of the hybrid scaffold of bioactive natural cinnamamide and heterocycle azetidi-2-one. The structures of
115. α-Methylidene-and α-alkylidene-β-lactams from nonproteinogenic amino acids
Buchholz, Rainer,Hoffmann, H. Martin R.
, p. 1213 - 1220 (2015/01/08)
Treatment of methyl 2-(l-hydroxyalkyl)prop-2-enoates1 with conc. HBr solution afforded methyl (Z)-2-(bromomethyl)alk-2-enoates 2, which were transformed regioselectively into N-substituted methyl (E)-2-(aminomethyl)alk-2-enoates 3 (SN2 reaction