137104-43-9Relevant articles and documents
Regio- and stereoselective synthesis of α,β amino esters
Li, Dafeng,Li, Jian,Jia, Xueshun
experimental part, p. 434 - 436 (2009/06/30)
A facile method for the regio- and stereoselective synthesis of α,β-dehydro-β-amino esters from acetates of Baylis- Hillman adducts with amines was reported. In the absence of any solvent and catalyst, the present strategy works well for a series of electron deficient and electron rich aromatic amines as well as aliphatic ones.
115. α-Methylidene-and α-alkylidene-β-lactams from nonproteinogenic amino acids
Buchholz, Rainer,Hoffmann, H. Martin R.
, p. 1213 - 1220 (2015/01/08)
Treatment of methyl 2-(l-hydroxyalkyl)prop-2-enoates1 with conc. HBr solution afforded methyl (Z)-2-(bromomethyl)alk-2-enoates 2, which were transformed regioselectively into N-substituted methyl (E)-2-(aminomethyl)alk-2-enoates 3 (SN2 reaction
