13713-79-6

Basic information

• Product Name: 5β-Cholestan-6-one
• Synonyms: Coprostan-6-one
• CAS NO: 13713-79-6
• Molecular Formula: C₂₇H₄₆O
• Molecular Weight: 0
• Mol File: 13713-79-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5β-Cholestan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5β-Cholestan-6-one(13713-79-6)
• EPA Substance Registry System: 5β-Cholestan-6-one(13713-79-6)

Safety Data

• Hazardous Substances Data: 13713-79-6(Hazardous Substances Data)

Upstream product

• 20248-32-2 coprostan-6β-ol 
• 109-63-7 trifluoroborane diethyl ether 
• 20230-22-2 5α,6α-epoxycholestane 
• 71-43-2 benzene 
• 566-30-3 Cholestane-5α,6α-diol 
• 570-46-7 5α-cholestan-6-one 
• 74770-57-3 6β-acetoxycholestan-3-one 
• 19043-46-0 5α-Cholest-4-en-6β-ol 
• 2542-92-9 acetic acid-(3β-hydroxy-5β-cholestanyl-(6β)-ester) 
• 2735-20-8 (5S,10R,13R,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-one oxime 
• 1912-53-4 (10R,13R,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-6-nitro-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene 

Downstream Products

• 570-46-7 5α-cholestan-6-one 

Relevant articles and documents

Reactions of epoxides-XXIV. The BF3-catalysed rearrangement of 4,5- and 5,6-epoxycholestanes

4α,5α, 4β,5β- and 5β, 6β-Epoxycholestanes give backbone rearranged compounds on BF3-catalysed rearrangement. Solvent changes markedly affect the products of rearrangement. 4α-Hydroxycompounds arise from the 4β,5β-epoxide on BF3-catal

Reactions of epoxides. XVII. "Backbone rearrangements" of cholest-5-ene and 5,6alpha-epoxy-5alpha-cholestane.

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Reactions of steroidal 5,6-epoxides and cyclohexene oxide with aluminum alkoxides

The isomeric 5,6α- and 5,6β-epoxycholestanes, in addition to an analogous series of compounds substituted at C-3 with hydroxy (α or β stereochemistry) or ethylene ketal groups, have been treated with aluminum isopropoxide or tert-butoxide.The latter series of reactions did not give identifiable material, but aluminum isopropoxide gave products derived from epoxide opening and rearrangement in all cases.With epoxides unsubstituted at C-3, aluminum isopropoxide functioned as a Lewis acid in promoting epoxide rearrangements.In the presence of a C-3 alcohol function, additional products were obtained arising from fragmentation of the C-4,C-5 bond, or from β-elimination of the epoxide involving the loss of a C-7 hydrogen.Meerwein-Pondorff reduction of product carbonyl groups was also observed.C-3 ketal substituted epoxides were rearranged cleanly to 6-hydroxy-Δ4-3-ketones.Cyclohexene oxide reacted with aluminum isopropoxide (but not with tert-butoxide) to give two products arising from epoxide addition reactions.Structures for these products are proposed based on their 13C nmr spectra, and a possible route for their formation is presented.None of the epoxides examined in this study reacted with magnesium methoxide.

Reactions with Phosphororganic Compounds XLVIII. On the Behaviour of cis-1,2-Diols towards TPP/DEAD

Reaction of the vicinal diols of steroids 1, 5, 7, 10, 13, and 16 with TPP/DEAD yields both regio- and stereospecifically the oxosteroids 2, 6, 8, 11, 14, and 15 by displacement of an axial hydrogen and extrusion of TPPO besides the cholest-4-en-6-ols 9 a