137225-10-6 Usage
General Description
2-[(3-fluorophenyl)amino]isonicotinonitrile is a chemical compound with the molecular formula C13H8FN3. It is a derivative of isonicotinonitrile and contains a fluorophenylamine group attached to the isonicotinonitrile ring. 2-[(3-fluorophenyl)amino]isonicotinonitrile has potential applications in medicinal chemistry and pharmaceutical research due to its structural features and potential biological activity. It is of interest for its potential pharmacological properties and may be used as a building block in the synthesis of other compounds with potential medicinal properties. Its structure makes it a valuable tool for the development of novel pharmacological agents.
Check Digit Verification of cas no
The CAS Registry Mumber 137225-10-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,2,2 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 137225-10:
(8*1)+(7*3)+(6*7)+(5*2)+(4*2)+(3*5)+(2*1)+(1*0)=106
106 % 10 = 6
So 137225-10-6 is a valid CAS Registry Number.
137225-10-6Relevant articles and documents
Efficient synthesis of 2-arylamino substituted pyridinyl nitriles by Buchwald-Hartwig amination
Guo, Shuo,Wang, Yaping,Sun, Chunxia,Li, Jingya,Zou, Dapeng,Wu, Yangjie,Wu, Yusheng
supporting information, p. 3233 - 3237 (2013/06/27)
Both nitrile and arylamino groups containing pyridine derivatives are synthesized from commercially available nitrile substituted pyridyl chlorides via a palladium-BINAP catalyst (the second generation catalyst for the amination) in moderate to good yields. The mild conditions permit the presence of base sensitive functional groups. Noteably, the halogen atoms linked to the aromatic ring were maintained in the structures of the products under the amination reaction conditions.
