1372868-35-3

Basic information

• Product Name: 2-chloro-N-((4-(trifluoromethoxy)phenyl)carbamoyl)-[carbonyl-⁽¹³⁾C]-benzamide
• Synonyms: 2-chloro-N-((4-(trifluoromethoxy)phenyl)carbamoyl)-[carbonyl-⁽¹³⁾C]-benzamide
• CAS NO: 1372868-35-3
• Molecular Weight: 359.693
• Mol File: 1372868-35-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-N-((4-(trifluoromethoxy)phenyl)carbamoyl)-[carbonyl-⁽¹³⁾C]-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-((4-(trifluoromethoxy)phenyl)carbamoyl)-[carbonyl-⁽¹³⁾C]-benzamide(1372868-35-3)
• EPA Substance Registry System: 2-chloro-N-((4-(trifluoromethoxy)phenyl)carbamoyl)-[carbonyl-⁽¹³⁾C]-benzamide(1372868-35-3)

Safety Data

• Hazardous Substances Data: 1372868-35-3(Hazardous Substances Data)

Upstream product

• 1072315-89-9 9-methylfluorene-9-([⁽¹³⁾C]-carbonyl) chloride 
• 615-41-8 2-iodochlorobenzene 
• 82971-90-2 1-(4-(trifluoromethoxy)phenyl)urea 

Relevant articles and documents

Palladium-catalyzed N -acylation of monosubstituted ureas using near-stoichiometric carbon monoxide

The palladium-catalyzed carbonylation of urea derivatives with aryl iodides and bromides afforded N-benzoyl ureas (20 examples) in yields attaining quantitative via the application of near-stoichiometric amounts of carbon monoxide generated from the decarbonylation of the CO precursor, 9-methylfluorene-9-carbonyl chloride. The synthetic protocol displayed good functional group tolerance. The methodology is also highly suitable for 13C isotope labeling, which was demonstrated through the synthesis of three benzoyl ureas, including the insecticide triflumuron, whereby 13CO was incorporated into the core structure.