1372892-90-4

Basic information

• Product Name: N-(4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)phenyl)picolinamide
• Synonyms: N-(4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)phenyl)picolinamide
• CAS NO: 1372892-90-4
• Molecular Weight: 403.824
• Mol File: 1372892-90-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)phenyl)picolinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)phenyl)picolinamide(1372892-90-4)
• EPA Substance Registry System: N-(4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)phenyl)picolinamide(1372892-90-4)

Safety Data

• Hazardous Substances Data: 1372892-90-4(Hazardous Substances Data)

Upstream product

• 98-98-6 2-Picolinic acid 
• 100-01-6 4-nitro-aniline 
• 61349-99-3 pyridine-2-carboxylic acid (4-nitro-phenyl)amide 
• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 491839-49-7 N-(4-aminophenyl)pyridine-2-carboxamide 

Relevant articles and documents

AMINONAPTHOQUINONE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR BLOCKING UBIQUITINATION-PROTEASOME SYSTEM IN DISEASES

The invention relates to new compounds with low cytotoxicity for blocking the ubiquitination-proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers, neurodegenerative diseas

Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors

Fourteen naphthoquinone derivatives (1-14) were designed based on a putative proteasome inhibitor PI-083. These compounds were synthesized and evaluated against A549, DU145, KB, and KBvin tumor cell lines. Six compounds (2, 4, 8, 9, 10, and 13) showed ant