1373215-32-7

Basic information

• Product Name: N-[(3R,4S)-6-bromo-3-hydroxy-chroman-4-yl]-4-fluoro-benzamide
• Synonyms: N-[(3R,4S)-6-bromo-3-hydroxy-chroman-4-yl]-4-fluoro-benzamide
• CAS NO: 1373215-32-7
• Molecular Weight: 366.187
• Mol File: 1373215-32-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(3R,4S)-6-bromo-3-hydroxy-chroman-4-yl]-4-fluoro-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(3R,4S)-6-bromo-3-hydroxy-chroman-4-yl]-4-fluoro-benzamide(1373215-32-7)
• EPA Substance Registry System: N-[(3R,4S)-6-bromo-3-hydroxy-chroman-4-yl]-4-fluoro-benzamide(1373215-32-7)

Safety Data

• Hazardous Substances Data: 1373215-32-7(Hazardous Substances Data)

Upstream product

• 70695-78-2 (3R,4S)-4-amino-6-bromochroman-3-ol 
• 403-43-0 4-fluorobenzoyl chloride 

Downstream Products

• 1373215-50-9 4-fluoro-N-((3R,4S)-3-hydroxy-6-(piperazin-1-yl)chroman-4-yl)benzamide 
• 1373215-45-2 4-fluoro-N-((3R,4S)-3-hydroxy-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-4-yl)benzamide 
• 1373215-15-6 (3R,4S)-4-(4-fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-3-yl methylcarbamate 

Relevant articles and documents

Cathepsin S Inhibitor Compounds

The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof. Also, the present invention provides a pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof with a pharmaceutically acceptable diluent or carrier. The present invention further provides methods for treating abdominal aortic aneurysm, plaque instability, atherosclerosis, or autoimmune disorders such as rheumatoid arthritis, psoriasis, and lupus comprising administering a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.