1373318-84-3 Usage
Description
Boceprevir Metabolite M4-d9 is a labeled metabolite derived from Boceprevir, which is an inhibitor of the Hepatitis C virus NS3 serine protease. This metabolite plays a significant role in the study and understanding of the drug's mechanism of action and its effects on the body.
Uses
Used in Pharmaceutical Research:
Boceprevir Metabolite M4-d9 is used as a research tool for understanding the metabolism and pharmacokinetics of Boceprevir. It helps researchers to study the drug's absorption, distribution, metabolism, and excretion (ADME) properties, which are crucial for drug development and optimization.
Used in Hepatitis C Treatment:
Boceprevir Metabolite M4-d9 is used as a component in the development of treatments for Hepatitis C virus (HCV) infections. By studying the metabolite, researchers can gain insights into the effectiveness of Boceprevir and its potential for improving patient outcomes in the treatment of HCV.
Used in Drug Interaction Studies:
Boceprevir Metabolite M4-d9 is used as a reference compound in drug interaction studies. Understanding how this metabolite interacts with other drugs can help researchers predict potential drug-drug interactions and develop strategies to minimize adverse effects or improve the efficacy of combination therapies.
Used in Quality Control:
Boceprevir Metabolite M4-d9 is used as a quality control standard in the manufacturing and testing of Boceprevir-containing pharmaceutical products. It ensures that the drug meets the required specifications and maintains a consistent level of quality throughout the production process.
Used in Analytical Chemistry:
Boceprevir Metabolite M4-d9 is used as a reference material in analytical chemistry for the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC) or mass spectrometry (MS). These methods are essential for the accurate quantification of Boceprevir and its metabolites in biological samples, which is crucial for pharmacokinetic studies and patient monitoring.
Check Digit Verification of cas no
The CAS Registry Mumber 1373318-84-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,3,3,1 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1373318-84:
(9*1)+(8*3)+(7*7)+(6*3)+(5*3)+(4*1)+(3*8)+(2*8)+(1*4)=163
163 % 10 = 3
So 1373318-84-3 is a valid CAS Registry Number.
1373318-84-3Relevant articles and documents
Synthesis of [14C]boceprevir, [13C 3]boceprevir, and [D9]boceprevir, a hepatitis C virus protease inhibitor
Ren, Sumei,Royster, Pernilla,Lavey, Carolee,Hesk, David,McNamara, Paul,Koharski, David,Truong, Van,Borges, Scott
scheme or table, p. 108 - 114 (2012/07/17)
Boceprevir is a hepatitis C virus (HCV) NS3 protease inhibitor for HCV treatment. [14C]Boceprevir (SCH 503034, trade name Victrelis) was synthesized from K14CN in 11 steps with an overall yield of 16.4%. [13C3]Boceprevir was synthesized in 16 steps with a 2.5% overall yield. The carbon-13 in the molecule was distributed along the peptide chain. [D9]Boceprevir was synthesized from [D9]-t- butylamine in four steps with an overall yield of 69%. Copyright 2012 John Wiley & Sons, Ltd. Boceprevir is an HCV NS3 protease inhibitor for HCV treatment. [14C]Boceprevir (SCH 503034, trade name Victrelis) was synthesized from K14CN in 11 steps with an overall yield of 16.4%. [13C3] Boceprevir was synthesized in 16 steps with a 2.5% overall yield. The carbon-13 in the molecule was distributed along the peptide chain. [D9]Boceprevir was synthesized from [D9]-t-butylamine in 4 steps with an overall yield of 69%.
