13734-08-2

Basic information

• Product Name: 2-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]ethanol
• CAS NO: 13734-08-2
• Molecular Formula: C₅H₆Cl₂N₄O
• Molecular Weight: 209.0333
• Mol File: 13734-08-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 454.9°C at 760 mmHg
• Flash Point: 228.9°C
• Density: 1.652g/cm³
• Vapor Pressure: 4.58E-09mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 2-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]ethanol(13734-08-2)
• EPA Substance Registry System: 2-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]ethanol(13734-08-2)

Safety Data

• Hazardous Substances Data: 13734-08-2(Hazardous Substances Data)

Usage

Physical form

white to off-white crystalline solid

Melting point

155-159°C

Stability

stable under normal conditions of use and storage

Uses

reagent for the synthesis of peptides and nucleotides, coupling agent in organic synthesis and chemical reactions, facilitator in the formation of amide bonds, production of pharmaceuticals, agrochemicals, and specialty chemicals

Toxicity

can be toxic if ingested or inhaled

Safety precautions

should be handled and stored with proper safety precautions in place

Role in industry

crucial in chemical and pharmaceutical industries as a versatile reagent in organic synthesis processes.

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 141-43-5 ethanolamine 

Downstream Products

• 24799-62-0 2-(4-anilino-6-chloro-[1,3,5]triazin-2-ylamino)-ethanol 

Relevant articles and documents

Double base compound based on phosphonitrile and triazine group and preparation method of double base compound

The invention discloses a double base compound based on phosphonitrile and triazine group. A preparation method of the double base compound comprises the following steps: introducing a triazine group into phosphonitrilic chloride trimer with intrinsically flame retardant property, and substituting six chlorine atoms on the side chains; further introducing a compound containing diamido or dyhydroxyl into the side chains of the triazine group, so as to obtain the double base compound based on phosphonitrile and triazine group. The compound is enriched in elements N and P; because the compound simultaneously contains the phosphonitrile and triazine group, the compound can achieve a flame-retardant effect in the combustion process by virtue of gas phase flame retardance and condensed phase mechanisms and has an excellent char-forming effect, and the generated carbon layer has the effects of insulating heat and inhibiting oxygen and achieves the effects of intumescent flame retardants. In addition, the phosphonitrile and triazine group have a synergistic flame retardant effect in the matrix combustion process. Moreover, the compound is high in heat stability, char-forming rate and processability and can be widely applied to flame-retardant modification of various high polymer materials.

Identification and optimization of inhibitors of trypanosomal cysteine proteases: Cruzain, rhodesain, and TbCatB

Trypanosoma cruzi and Trypanosoma brucei are parasites that cause Chagas' disease and African sleeping sickness, respectively. Both parasites rely on essential cysteine proteases for survival: cruzain for T. cruzi and TbCatB/rhodesain for T. brucei. A rec