1373432-34-8

Basic information

• Product Name: (R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide
• Synonyms: (R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide
• CAS NO: 1373432-34-8
• Molecular Weight: 346.363
• Mol File: 1373432-34-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide(1373432-34-8)
• EPA Substance Registry System: (R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide(1373432-34-8)

Safety Data

• Hazardous Substances Data: 1373432-34-8(Hazardous Substances Data)

Upstream product

• 1202032-99-2 (R)-3-(tert-butyl)-3-oxido-2H-benzo[d][1,3]oxaphosphol-4-yl trifluoromethanesulfonate 
• 151-10-0 1,3-Dimethoxybenzene 
• 23112-96-1 (2,6-dimethoxyphenyl)boronic acid 

Downstream Products

• 1246888-90-3 (S)-3-tert-butyl-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole 
• 1373432-38-2 (2S,3R)-2-benzyl-3-tert-butyl-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole oxide 
• 1373432-13-3 C₂₆H₂₉O₃P 
• 1373432-41-7 C₃₀H₃₁O₄P 
• 1373432-15-5 C₃₀H₃₁O₃P 
• 1477517-21-7 C₂₂H₂₉O₃P 
• 2247162-97-4 C₂₁H₂₇O₃P 

Relevant articles and documents

Synthesis of P-Chiral Dihydrobenzooxaphospholes Through Negishi Cross-Coupling

An efficient Negishi cross-coupling was developed for the synthesis of the biaryl axes present in useful P-chiral dihydrobenzooxaphosphole ligands. This approach has allowed for the synthesis of new derivatives of these ligands that were not accessible by the previous route employing Suzuki-Miyaura cross-coupling. The use of Pd2(dba)3/BI-DIME as the catalyst system affords the desired biaryl compounds in good yields with excellent rates and with catalyst loadings as low as 0.25 mol %.