137354-54-2 Usage
General Description
Quinoline, 4-(bromomethyl)-2-chloro- is a chemical compound with the molecular formula C10H8BrClN. It is a yellow to brown solid substance and is commonly used in the synthesis of pharmaceuticals, dyes, and agrochemicals. Quinoline, 4-(bromomethyl)-2-chloro- is also known for its use in the production of antimalarial drugs. However, it is important to handle this chemical with caution as it is a potential irritant to the skin, eyes, and respiratory system. Furthermore, it may also pose environmental hazards if not properly managed and disposed of.
Check Digit Verification of cas no
The CAS Registry Mumber 137354-54-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,3,5 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 137354-54:
(8*1)+(7*3)+(6*7)+(5*3)+(4*5)+(3*4)+(2*5)+(1*4)=132
132 % 10 = 2
So 137354-54-2 is a valid CAS Registry Number.
137354-54-2Relevant articles and documents
Synthesis and antiulcer activity of optical isomers of 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid (Rebamipide)
Otsubo,Morita,Uchida,Yamasaki,Kanbe,Shimizu
, p. 2906 - 2909 (1991)
The enantiomers of 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid [(±)-1, rebamipide, OPC-12759], a new antiulcer agent that enhances mucosal resistance, were synthesized from optically active α-amino acid derivatives of 2(1H)-quinolinone. The key intermediates, α-amino acid derivatives, were prepared by asymmetric synthesis and optical resolution. The (±)-1 was ahout 1.7 times as potent as the (-)-isomer in antiulcer activity against ethanol-induced gastric ulcers.
