1373883-97-6

Basic information

• Product Name: 3-(3-(4-fluorophenyl)-1,1-diphenylprop-2-yn-1-yl)-1-methyl-1H-indole
• CAS NO: 1373883-97-6
• Molecular Weight: 415.51
• Mol File: 1373883-97-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-(4-fluorophenyl)-1,1-diphenylprop-2-yn-1-yl)-1-methyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-(4-fluorophenyl)-1,1-diphenylprop-2-yn-1-yl)-1-methyl-1H-indole(1373883-97-6)
• EPA Substance Registry System: 3-(3-(4-fluorophenyl)-1,1-diphenylprop-2-yn-1-yl)-1-methyl-1H-indole(1373883-97-6)

Safety Data

• Hazardous Substances Data: 1373883-97-6(Hazardous Substances Data)

Upstream product

• 603-76-9 1-methylindole 
• 1192167-43-3 1,1-diphenyl-3-p-fluorophenylpropargyl alcohol 

Relevant articles and documents

3-alkenylation or 3-alkylation of indole with propargylic alcohols: Construction of 3,4-dihydrocyclopenta[ b ]indole and 1,4-dihydrocyclopenta[ b ]indole in the presence of different catalysts

3-Alkenylation or 3-alkylation of indole with propargylic alcohols could be efficiently controlled by the catalyst. In the presence of triflic acid, 3-alkenylation of indole occurred and a 3,4-dihydrocyclopenta[b]indole skeleton was effectively constructed in moderate to excellent yields via a cascade process. In the presence of Cu(OTf)2, 3-alkylation of indole resulted in the formation of 3-propargylic indole, which could be further converted into 2-iodo-1,4-dihydrocyclopenta[b]indoles in the presence of N-iodosuccinimide and boron trifluoride etherate. Possible mechanisms related to the 3-alkenylation or 3-alkylation of indole and their extension to the formation of 3,4-dihydrocyclopenta[b]indoles or 1,4-dihydrocyclopenta[b]indoles are postulated and discussed.