1373884-03-7

Basic information

• Product Name: 2-iodo-4-methyl-3-phenyl-4H-spiro[cyclopenta[b]indole-1,9′-fluorene]-7-carbonitrile
• CAS NO: 1373884-03-7
• Molecular Weight: 546.41
• Mol File: 1373884-03-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-iodo-4-methyl-3-phenyl-4H-spiro[cyclopenta[b]indole-1,9′-fluorene]-7-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-4-methyl-3-phenyl-4H-spiro[cyclopenta[b]indole-1,9′-fluorene]-7-carbonitrile(1373884-03-7)
• EPA Substance Registry System: 2-iodo-4-methyl-3-phenyl-4H-spiro[cyclopenta[b]indole-1,9′-fluorene]-7-carbonitrile(1373884-03-7)

Safety Data

• Hazardous Substances Data: 1373884-03-7(Hazardous Substances Data)

Upstream product

• 117745-96-7 9-phenylethynylfluoren-9-ol 
• 91634-11-6 N-methyl-5-cyanoindole 

Relevant articles and documents

3-alkenylation or 3-alkylation of indole with propargylic alcohols: Construction of 3,4-dihydrocyclopenta[ b ]indole and 1,4-dihydrocyclopenta[ b ]indole in the presence of different catalysts

3-Alkenylation or 3-alkylation of indole with propargylic alcohols could be efficiently controlled by the catalyst. In the presence of triflic acid, 3-alkenylation of indole occurred and a 3,4-dihydrocyclopenta[b]indole skeleton was effectively constructed in moderate to excellent yields via a cascade process. In the presence of Cu(OTf)2, 3-alkylation of indole resulted in the formation of 3-propargylic indole, which could be further converted into 2-iodo-1,4-dihydrocyclopenta[b]indoles in the presence of N-iodosuccinimide and boron trifluoride etherate. Possible mechanisms related to the 3-alkenylation or 3-alkylation of indole and their extension to the formation of 3,4-dihydrocyclopenta[b]indoles or 1,4-dihydrocyclopenta[b]indoles are postulated and discussed.