13739-49-6Relevant articles and documents
FERROPORTIN INHIBITORS AND METHODS OF USE
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Paragraph 0686; 0687, (2020/07/07)
The subject matter described herein is directed to Ferroportin inhibitor compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis.
Highly efficient and eco-friendly protocol to functionalized imidazoles via ring-opening of α-nitro epoxides
Guo, Xiao,Shao, Jiaan,Liu, Huan,Chen, Binhui,Chen, Wenteng,Yu, Yongping
, p. 51559 - 51562 (2015/06/25)
A simple and direct synthesis of functionalized imidazoles from α-nitro-epoxides and amidines was developed. This reaction could proceed smoothly in a highly efficient and eco-friendly manner in moderate to excellent yields. A plausible mechanism has also
Hypervalent iodine in synthesis 81: A one-pot procedure for the synthesis of 1H-imidazole derivatives by cyclocondensation of ketones with [Hydroxy(tosyloxy)iodo]benzene and amidines
Zhang,Chen
, p. 2075 - 2077 (2007/10/03)
Tosyloxylation of ketones with [hydroxy(tosyloxy)iodo]benzene (HTIB), followed by treatment with amidines provides a one-pot procedure for the synthesis of 1H-imidazole derivatives with good yields.