13745-42-1

Basic information

• Product Name: 1H-Benzimidazole-2-carboxamide, N-phenyl-
• CAS NO: 13745-42-1
• Molecular Formula: C14H11N3O
• Molecular Weight: 237.261
• Mol File: 13745-42-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Benzimidazole-2-carboxamide, N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-2-carboxamide, N-phenyl-(13745-42-1)
• EPA Substance Registry System: 1H-Benzimidazole-2-carboxamide, N-phenyl-(13745-42-1)

Safety Data

• Hazardous Substances Data: 13745-42-1(Hazardous Substances Data)

Upstream product

• 103-71-9 phenyl isocyanate 
• 19213-18-4 1-pyrrolidin-1-ylmethyl-1H-benzoimidazole 
• 90430-71-0 N-phenyl-1H-benzo[d]imidazole-2-carbothioamide 
• 4857-04-9 2-chloromethyl-1H-benzimidazole 
• 62-53-3 aniline 
• 127427-45-6 2-bromo-2,2-difluoro-N-phenyl-acetamide 
• 95-54-5 1,2-diamino-benzene 
• 88-74-4 2-nitro-aniline 
• 897583-89-0 N-(2-nitrophenyl)-2-phenylamino-2-thioxoacetamide 
• 10147-70-3 2-chloro-N-(2-nitrophenyl)acetamide 
• 10543-64-3 phenyl-oxalamide 
• 51-17-2 benzoimidazole 
• 98-95-3 nitrobenzene 

Relevant articles and documents

Desulfurizing agent for thioamides

Thioamides treated with thionyl chloride in an ionic liquid were successfully converted into amides.

HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE

Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being described in the specifications. The compound represented by formula (I) can be used as the ligand in the copper catalyzed coupling reaction of the aryl halogeno substitute, and is used or catalyzing the coupling reaction for forming the aryl halogeno substitute having C—N, C—O, C—S and other bonds.

Synthesis of 2-Substituted Imidazoles and Benzimidazoles and of 3-Substituted Pyrazoles by Lithiation of N-(Dialkylamino)methyl Heterocycles

The lithiation of N-(dialkylamino)methyl (aminal) derivatives of imidazole, benzimidazole, and pyrazole (themselves readily available from parent heterocycles, formaldehyde, and a secondary amine) occurs smoothly at 2-, 2-, and 5-positions, respectively, upon treatment with n-butyllithium in ether or tetrahydrofuran.Reaction with electrophiles, and subsequent facile acid-catalyzed hydrolysis of the protecting group, provides 2-substituted imidazoles, 2-substituted benzimidazoles, and 3(5)-substituted pyrazoles in good overall yields.