1374863-09-8

Basic information

• Product Name: 2-(trifluoromethyl)-6-(4-((3-(trifluoromethyl)phenyl)sulfonyl)benzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
• Synonyms: 2-(trifluoromethyl)-6-(4-((3-(trifluoromethyl)phenyl)sulfonyl)benzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
• CAS NO: 1374863-09-8
• Molecular Weight: 500.421
• Mol File: 1374863-09-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(trifluoromethyl)-6-(4-((3-(trifluoromethyl)phenyl)sulfonyl)benzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(trifluoromethyl)-6-(4-((3-(trifluoromethyl)phenyl)sulfonyl)benzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one(1374863-09-8)
• EPA Substance Registry System: 2-(trifluoromethyl)-6-(4-((3-(trifluoromethyl)phenyl)sulfonyl)benzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one(1374863-09-8)

Safety Data

• Hazardous Substances Data: 1374863-09-8(Hazardous Substances Data)

Upstream product

• 1374864-78-4 4-((3-(trifluoromethyl)phenyl)sulfonyl)benzonitrile 
• 1374864-77-3 4-(3-(trifluoromethyl)phenylthio)benzonitrile 
• 937-00-8 3-trifluoromethyl-thiophenol 
• 380355-61-3 ethyl 2-(bromomethyl)-6-(trifluoromethyl)nicotinate 
• 1374864-79-5 (4-((3-(trifluoromethyl)phenyl)sulfonyl)phenyl)methanamine 
• 261635-93-2 2-methyl-6-(trifluoromethyl)pyridine-3-carboxylic acid 
• 1194-02-1 4-fluorobenzonitrile 

Relevant articles and documents

BISARYLSULFONE AND DIALKYLARYLSULFONE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS

The invention relates to bisarylsulfone and dialkylarylsulfone compounds (e.g., compounds according to any of Formulas (I)-(IX) or compounds (1)-(227) of Tables 4 and 5) useful in treating conditions associated with calcium channel function, and particularly conditions associated with N-type calcium channel activity. The invention also relates to pharmaceutical compositions that include these bisarylsulfone compounds, as well methods for the treatment of conditions such as cardiovascular disease, epilepsy, cancer and pain.