1374988-79-0

Basic information

• Product Name: (R)-3-[5-methyl-2-((E)-2-(4-methylphenyl)ethenyl)phenyl]cyclohexanone
• Synonyms: (R)-3-[5-methyl-2-((E)-2-(4-methylphenyl)ethenyl)phenyl]cyclohexanone
• CAS NO: 1374988-79-0
• Molecular Weight: 304.432
• Mol File: 1374988-79-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-[5-methyl-2-((E)-2-(4-methylphenyl)ethenyl)phenyl]cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-[5-methyl-2-((E)-2-(4-methylphenyl)ethenyl)phenyl]cyclohexanone(1374988-79-0)
• EPA Substance Registry System: (R)-3-[5-methyl-2-((E)-2-(4-methylphenyl)ethenyl)phenyl]cyclohexanone(1374988-79-0)

Safety Data

• Hazardous Substances Data: 1374988-79-0(Hazardous Substances Data)

Upstream product

• 2378-86-1 4-methylbenzyltriphenylphosphonium bromide 
• 38424-23-6 (E)-4,4'-dimethylstilbene 
• 1588-49-4 4,4'-dimethylstilbene 
• 930-68-7 cyclohexenone 
• 1374989-07-7 (E)-1,2-di(4-methylphenyl)ethenylboronic acid 

Relevant articles and documents

Asymmetric conjugate addition of cis-2-arylethenylboronic acids catalyzed by chiral diene/rhodium complexes: 1,4-rhodium shift from alkenylrhodium to arylrhodium intermediates

The reaction of (E)-1,2-diphenylethenylboronic acid 1 with 2-cyclohexenone in the presence of a chiral diene/rhodium catalyst (5 mol %) gave 3-[2-((E)-2-phenylethenyl)phenyl]cyclohexanone in 99% yield with 98.7% ee; the catalytic cycle involves a 1,4-rhodium shift from a 2-phenylethenylrhodium to an ortho-alkenylphenylrhodium intermediate. In the reaction of 1 with (E)-1-phenyl-2-buten-1-one, either the tandem 1,4-shift/arylation product or the direct alkenylation product is formed selectively by an appropriate choice of chiral diene ligand.