1375100-74-5

Basic information

• Product Name: 3-((3-hydroxy-4-methoxybenzylidene)hydrazinocarbonyl)-7-(N'-(3-hydroxy-4-methoxybenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one
• CAS NO: 1375100-74-5
• Molecular Weight: 559.554
• Mol File: 1375100-74-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((3-hydroxy-4-methoxybenzylidene)hydrazinocarbonyl)-7-(N'-(3-hydroxy-4-methoxybenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((3-hydroxy-4-methoxybenzylidene)hydrazinocarbonyl)-7-(N'-(3-hydroxy-4-methoxybenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one(1375100-74-5)
• EPA Substance Registry System: 3-((3-hydroxy-4-methoxybenzylidene)hydrazinocarbonyl)-7-(N'-(3-hydroxy-4-methoxybenzylidene)hydrazino)-1-cycloproyl-6-fluoroquinolin-4(1H)-one(1375100-74-5)

Safety Data

• Hazardous Substances Data: 1375100-74-5(Hazardous Substances Data)

Upstream product

• 86483-54-7 ethyl 1-cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylate 
• 621-59-0 isovanillin 
• 1375100-68-7 C₁₃H₁₄FN₅O₂ 

Relevant articles and documents

Synthesis and antitumor and antibacterial evaluation of fluoro-quinolone derivatives (III): Mono- and bis-Schiff-bases

To further explore an efficient modified route for the shift from an antibacterial fluoroquinolone to an antitumor one, mono-Schiff bases 6a-6h related to ciprofloxacin C3 carbonylhydrazone and bis-Schiff bases 4a-4h corresponding to C3/C7 carbonylhydrazone/hydrazone attached on a skeleton of ciprofloquinolone were designed and synthesized, and their in vitro antitumor activity against CHO, HL60, L1210 cells and antibacterial activity against Staphylococcus aureus and Escherichia coli were also reported.