137531-66-9Relevant articles and documents
New General Approach to the Synthesis of Yuehchukene Analogues. Stereoselective Synthesis of 9,10-Dihydro-7α,9-didemethylyuehchukene. X-Ray Molecular Structure of 6β-(Indol-3'-yl)-7β-methyl-5-phenylsulphonyl-5,6,6aβ,7,8,9,10,10aβ-octahydroindenoindole
Cheng, Kin-Fai,Chan, Kwok-Pong,Lai, Ting-Fong
, p. 2461 - 2465 (2007/10/02)
A versatile synthetic strategy for the syntheses of the yuehchukene analogues 6β-(indol-3'-yl)-7β-methyl-5,6,6aβ,7,8,9,10,10aβ-octahydroindenoindole and 7β-methyl-6β-(2'-methylindol-3'-yl)-5,6,6aβ,7,8,9,10,10aβ-octahydroindenoindole is described.The key reactions involve trapping of the vinyllithium derivative 6-methylcyclohex-1-enyllithium, generated from the trisylhydrazone of 2-methylcyclohexanone, with indole-2-carbaldehyde, and Nazarov cyclization of the α,β-unsaturated 2-acylindole 6-methylcyclohex-1-enyl N-phenylsulphonylindol-2-yl ketone.