137531-98-7Relevant articles and documents
A Formal Synthesis of Aplysiatoxin: Enantioselective Synthesis of Kishi's Aldehyde
Okamura, Hiroaki,Kuroda, Satoru,Ikegami, Satoru,Tomita, Kenji,Sugimoto, Yu-ichi,et al.
, p. 10531 - 10554 (2007/10/02)
This paper describes the enantioselective synthesis of key fragments (12,18,24, and 35) for the synthesis of aplysiatoxin (1a), a potent cancer promoter, and their convergent assembly to Kishi's aldehyde (2).Since 2 has already been transformed into 1a in