1375314-05-8

Basic information

• Product Name: 1,3-bis[N'-(4-chlorophenylsulfonyl)-N-methyl-(S)-prolinamidomethyl]-1,1,3,3-tetramethyl-1,3-disiloxane
• Synonyms: 1,3-bis[N'-(4-chlorophenylsulfonyl)-N-methyl-(S)-prolinamidomethyl]-1,1,3,3-tetramethyl-1,3-disiloxane
• CAS NO: 1375314-05-8
• Molecular Weight: 763.911
• Mol File: 1375314-05-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-bis[N'-(4-chlorophenylsulfonyl)-N-methyl-(S)-prolinamidomethyl]-1,1,3,3-tetramethyl-1,3-disiloxane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis[N'-(4-chlorophenylsulfonyl)-N-methyl-(S)-prolinamidomethyl]-1,1,3,3-tetramethyl-1,3-disiloxane(1375314-05-8)
• EPA Substance Registry System: 1,3-bis[N'-(4-chlorophenylsulfonyl)-N-methyl-(S)-prolinamidomethyl]-1,1,3,3-tetramethyl-1,3-disiloxane(1375314-05-8)

Safety Data

• Hazardous Substances Data: 1375314-05-8(Hazardous Substances Data)

Upstream product

• 73096-27-2 N-(4-chlorophenylsulfonyl)-(S)-proline 

Relevant articles and documents

Pentacoordinated chlorosilanes with C,O-chelate ligands derived from N-methyl-N’-organosulfonyl-prolinamides

The reaction of amides RSO2-Pro-NHMe with ClCH2SiMe2Cl in the presence of (Me3Si)2NH gave pentacoordinatedchlorosilanes RSO2-Pro-N(Me)CH2SiMe2Cl with an organosulfonyl group (R = Me, Ph, 4-ClC6H4, 4-BrC6H4, 4-MeC6H4, and 4-O2NC6H4) attached to the proline nitrogen atom. An alternative method for the preparation of these compounds comprises the cyclosilylmethylation of proline methylamide by dimethylchloromethylchlorosilane to give the previously unreported heterocyclic 2-sila-5-piperazinone system in the first step. The bicyclic silacyclane synthesized is 2-sila-5-piperazinone condensed with a proline residue. The action of sulfonyl chlorides RSO2Cl leads to cleavage of the sila ring Si–N bond to give the desired chlorosilanes. The hydrolysis of these products, depending on the reaction conditions, gives either silyloxonium chlorides [RSO2-Pro-N(Me)CH2SiMe2OH2]Cl or disiloxanes [RSO2-Pro-N(Me)CH2SiMe2]2O. X-ray diffraction structural analysis showed that the silicon atom in the chlorides and silyloxonium chlorides is pentacoordinated due to an intramolecular O→Si bond and has distorted trigonal-bipyrimidal configuration.29Si NMR spectroscopy showed that the disiloxanes and bicyclic sila-5-piperazinone have a tetracoordinated silicon atom.