1375693-06-3

Basic information

• Product Name: (4-bromo-2-fluorobenzyl) 3-O-(4-oxo-4H-1-benzopyran-2-carbonyl)-olean-12-en-30-oate
• Synonyms: (4-bromo-2-fluorobenzyl) 3-O-(4-oxo-4H-1-benzopyran-2-carbonyl)-olean-12-en-30-oate
• CAS NO: 1375693-06-3
• Molecular Weight: 815.86
• Mol File: 1375693-06-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-bromo-2-fluorobenzyl) 3-O-(4-oxo-4H-1-benzopyran-2-carbonyl)-olean-12-en-30-oate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromo-2-fluorobenzyl) 3-O-(4-oxo-4H-1-benzopyran-2-carbonyl)-olean-12-en-30-oate(1375693-06-3)
• EPA Substance Registry System: (4-bromo-2-fluorobenzyl) 3-O-(4-oxo-4H-1-benzopyran-2-carbonyl)-olean-12-en-30-oate(1375693-06-3)

Safety Data

• Hazardous Substances Data: 1375693-06-3(Hazardous Substances Data)

Upstream product

• 6894-46-8 11-deoxyglycyrrhetinic acid 
• 471-53-4 enoxolone 
• 4940-39-0 acide chromone carboxylique-2 
• 1375692-82-2 (4-bromo-2-fluorobenzyl) 3β-hydroxy-olean-12-en-30-oate 

Relevant articles and documents

Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents

Fifty-seven derivatives of glycyrrhetinic acid (GA) were synthesized, and their anti-hepatitis B virus (HBV) activity was evaluated in HepG 2.2.15 cells. Among them, sixteen compounds showed greater anti-HBV activity than GA, especially, compounds 29, 32, 35, 41 exhibited significantly inhibitory activities against HBV DNA replication with IC50 values of 5.71, 5.36, 8.90 and 9.08 μM, respectively. The structure-activity relationships (SARs) of GA derivatives were discussed for exploring novel anti-HBV agents.