137570-75-3

Basic information

• Product Name: 1-(bromomethyl)-3,5-dinitrobenzene
• Synonyms: 1-(bromomethyl)-3,5-dinitrobenzene
• CAS NO: 137570-75-3
• Molecular Formula: C₇H₅BrN₂O₄
• Molecular Weight: 261.0296
• Mol File: 137570-75-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 65-66 °C
• Boiling Point: 177 °C
• Appearance: /
• Density: 1.830±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-(bromomethyl)-3,5-dinitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(bromomethyl)-3,5-dinitrobenzene(137570-75-3)
• EPA Substance Registry System: 1-(bromomethyl)-3,5-dinitrobenzene(137570-75-3)

Safety Data

• Hazardous Substances Data: 137570-75-3(Hazardous Substances Data)

Usage

Family

Nitrobenzene family

Structural features

Presence of a bromomethyl group
Two nitro groups on a benzene ring

Applications

Organic synthesis
Starting material for dyes and pigments production

Reactivity

Reacts with nucleophiles
Useful in forming carbon-carbon and carbon-heteroatom bonds

Potential uses

Pesticidal properties
Herbicidal properties

Safety

Toxic compound
Requires careful handling

Upstream product

• 618-85-9 3,5-dinitrotoluene 
• 71022-43-0 3,5-dinitrobenzyl alcohol 
• 99-34-3 3,5-dinitrobenzoic acid 

Downstream Products

• 125996-94-3 1-(3,5-Dinitro-benzyl)-4-(2-oxo-2-phenyl-ethyl)-pyridinium; bromide 
• 192137-08-9 3,5-dinitrobenzyl iodide 
• 371979-30-5 (2R,4R)-4-tert-Butoxycarbonylamino-1-(3,5-dinitro-benzyl)-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 70136-12-8 (3,5-dinitrophenyl)nitromethane 
• 1312023-62-3 1-(2,2,2-trifluoroethyl)-3,5-dinitrobenzene 
• 1384113-73-8 leubethanol 3,5-dinitrobenzyl ether 
• 1384113-68-1 5-(3,5-dinitrobenzyl)leubethanol 
• 1448147-86-1 3,5-dinitrobenzylbromide 
• 1448147-87-2 trolox 
• 1448147-89-4 C₄₆H₅₆N₄O₁₆S₂ 
• 1448147-90-7 C₅₀H₅₉N₅O₁₈S₂ 
• 1133862-70-0 3,5-dinitrobenzylazide 

Relevant articles and documents

Solvent Effects on Proton Transfer Reactions: Benzoate Ion Promoted Deprotonation Reactions of Arylnitromethanes in Methanol Solution

Second-order rate constants and equilibrium constants have been determined for the benzoate ion promoted deprotonation reactions of (m-nitrophenyl)nitromethane, (p-nitrophenyl)nitromethane, and (3,5-dinitrophenyl)nitromethane in methanol solution. The pK

Inhibition of M. tuberculosis β-ketoacyl CoA reductase FabG4 (Rv0242c) by triazole linked polyphenol-aminobenzene hybrids: Comparison with the corresponding gallate counterparts

Herein we report six novel triazole linked polyphenol-aminobenzene hybrids (3-8) as inhibitors of Mycobacterium tuberculosis FabG4 (Rv0242c), a less explored β-ketoacyl CoA reductase that has immense potential to be the future anti-tuberculosis drug target due to its possible involvement in drug resistance and latent infection. Novel triazole linked polyphenol-aminobenzene hybrids have been synthesized, characterized and evaluated for their inhibitory activity against FabG4. All of them inhibit FabG4 at low micromolar concentrations. In silico docking study has been carried out to explain the experimental findings. A comparative study of these new inhibitors with previously reported gallate counterparts leads to structure-activity relations (SAR) of substituent linked to N-1 of triazole ring.

Perfluoroalkylated amines, and polymers made therefrom

1-[2,2-bis(trifluoromethyl)-3,3,4,4,5,5,5-heptafluoropentyl]-3,5-diaminobenzene and 1-[2,2-bis(trifluoromethyl)-3,3,4,4,5,5,5-heptafluoropentyl]-4-aminobenzene, as well as fluorinated polymers, preferably polyimides. The perfluoroalkyl group of these amin