137571-76-7

Basic information

• Product Name: 4H-1,3-Benzodioxin-4-one, 5-(1-heptynyl)-2,2-dimethyl-7-(phenylmethoxy)-
• CAS NO: 137571-76-7
• Molecular Formula: C24H26O4
• Molecular Weight: 378.468
• Mol File: 137571-76-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4H-1,3-Benzodioxin-4-one, 5-(1-heptynyl)-2,2-dimethyl-7-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Benzodioxin-4-one, 5-(1-heptynyl)-2,2-dimethyl-7-(phenylmethoxy)-(137571-76-7)
• EPA Substance Registry System: 4H-1,3-Benzodioxin-4-one, 5-(1-heptynyl)-2,2-dimethyl-7-(phenylmethoxy)-(137571-76-7)

Safety Data

• Hazardous Substances Data: 137571-76-7(Hazardous Substances Data)

Upstream product

• 628-71-7 1-Heptyne 
• 137571-74-5 7-(benzyloxy)-5-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 137571-73-4 5,7-dihydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 83-30-7 acide 2,4,6-trihydroxybenzoique 
• 137571-75-6 7-(benzyloxy)-2,2-dimethyl-5-<(trifluoromethyl)sulfonyl>-4H-1,3-benzodioxin-4-one 

Downstream Products

• 1408253-08-6 2,4-bis(benzyloxy)-6-heptylbenzoic acid 
• 1408253-05-3 benzyl 2,4-bis(benzyloxy)-6-heptylbenzoate 
• 1408253-09-7 benzyl 4-((2,4-bis(benzyloxy)-6-heptylbenzoyl)oxy)-2-heptyl-6-hydroxybenzoate 
• 137571-94-9 ent-KS-501 
• 120634-86-8 KS-501 
• 137571-93-8 3'-(benzyloxy)-6'-<<4''-<(benzyloxy)carbonyl>-5''-(1-heptyl)-3''-hydroxyphenoxy>carbonyl>-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-L-galactofuranoside 
• 137571-85-8 3'-(benzyloxy)-6'-<<4''-<(benzyloxy)carbonyl>-5''-(1-heptyl)-3''-hydroxyphenoxy>carbonyl>-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-D-galactofuranoside 
• 137571-92-7 3'-(benzyloxy)-6'-<<5''-(1-heptyl)-3''-hydroxyphenoxy>carbonyl>-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-L-galactofuranoside 
• 137571-84-7 3'-(benzyloxy)-6'-<<5''-(1-heptyl)-3''-hydroxyphenoxy>carbonyl>-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-D-galactofuranoside 
• 137571-82-5 3'-(benzyloxy)-6'-<<β-(trimethylsilyl)ethoxy>carbonyl>-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-5,6-cyclopentylidene-D-galactofuranoside 
• 137571-90-5 3'-(benzyloxy)-6'-<<β-(trimethylsilyl)ethoxy>carbonyl>-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-5,6-cyclopentylidene-L-galactofuranoside 
• 137571-83-6 3'-(benzyloxy)-6'-carboxy-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-5,6-cyclopentylidene-D-galactofuranoside 
• 137571-91-6 3'-(benzyloxy)-6'-carboxy-5'-(1-heptyn-1-yl)phenyl 2,3-di-O-benzyl-5,6-cyclopentylidene-L-galactofuranoside 
• 137571-81-4 3'-(benzyloxy)-6'-<<β-(trimethylsilyl)ethoxy>carbonyl>-5'-(1-heptyn-1-yl)phenyl 3-O-benzyl-5,6-cyclopentylidene-D-galactofuranoside 

Relevant articles and documents

Total syntheses of KS-501, KS-502, and their enantiomers

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Synthesis of inhibitors of calmodulin-mediated enzymes including KS-501, KS-502 and their enantiomers

The total synthesis of a group of compounds with inhibitory effects on calmodulin-mediated enzyme activities has been accomplished. Among these synthesized compounds are KS-501 and KS-502. Other compounds that have been synthesized by the described scheme are ent-KS-501 and ent-KS-502 which are enantiomers of KS-501 and KS-502 and which also have inhibitory effects on calmodulin-mediated enzyme activities.