1376377-42-2Relevant articles and documents
Growth inhibition of Mycobacterium smegmatis by prodrugs of deoxyxylulose phosphate reducto-isomerase inhibitors, promising anti-mycobacterial agents
Ponaire, Sarah,Zinglé, Catherine,Tritsch, Denis,Grosdemange-Billiard, Catherine,Rohmer, Michel
experimental part, p. 277 - 285 (2012/07/14)
Since Mycobacterium tuberculosis sets up several multiple anti-tuberculosis drug resistance mechanisms, development of new drugs with innovative target is urgent. The methylerythritol phosphate pathway (MEP) involved in the biosynthesis of essential metab