137649-36-6

Basic information

• Product Name: N-phthaloyl-(S)-tert-leucine methyl ester
• CAS NO: 137649-36-6
• Molecular Weight: 275.304
• Mol File: 137649-36-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-phthaloyl-(S)-tert-leucine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-phthaloyl-(S)-tert-leucine methyl ester(137649-36-6)
• EPA Substance Registry System: N-phthaloyl-(S)-tert-leucine methyl ester(137649-36-6)

Safety Data

• Hazardous Substances Data: 137649-36-6(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 63038-26-6 (S)-2-amino-3,3-dimethyl-butyric acid methyl ester 
• 186581-53-3 diazomethane 
• 142765-23-9 (S)-(-)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3,3-dimethyl-butyric acid 
• 22509-74-6 N-ethoxycarbonylphthalimide 
• 63038-27-7 L-tert-leucine methyl ester hydrochloride 
• 20859-02-3 L-tert-Leucine 

Relevant articles and documents

Amplification of the chiroptical response of UV-Transparent amines and alcohols by: N-phthalimide derivatization enabling absolute configuration determination through ECD computational analysis

The stereoselective transformation of chiral UV-Transparent amines and alcohols to phthalimides has proved to be a simple and efficient method to enhance the chiroptical response of these substrates allowing their reliable absolute configuration determination by computational analysis of ECD spectra. Such a transformation also leads to a significant reduction in the molecular conformational flexibility thus simplifying the conformational analysis required by the computational treatment. The method described herein thus allows the absolute configuration assignment to these challenging substrates to be much easier and reliable.

Photochemie von N-Phthaloyl-α-aminosaeureestern: Ein neuer Zugang zu β,γ-ungesaettigten α-Aminosaeuren und Dihydrobenzazepindionen

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