137649-65-1

Basic information

• Product Name: Carbamic acid, [1-formyl-3-(methylthio)propyl]-, phenylmethyl ester, (S)-
• CAS NO: 137649-65-1
• Molecular Formula: C13H17NO3S
• Molecular Weight: 267.349
• Mol File: 137649-65-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [1-formyl-3-(methylthio)propyl]-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [1-formyl-3-(methylthio)propyl]-, phenylmethyl ester, (S)-(137649-65-1)
• EPA Substance Registry System: Carbamic acid, [1-formyl-3-(methylthio)propyl]-, phenylmethyl ester, (S)-(137649-65-1)

Safety Data

• Hazardous Substances Data: 137649-65-1(Hazardous Substances Data)

Upstream product

• 56762-93-7 methyl (S)-2-(benzyloxycarbonylamino)-4-methylmercaptobutanoate 
• 1205674-06-1 (S)-benzyl {1-[methoxy(methyl)amino]-4-(methylthio)-1-oxobutan-2-yl}carbamate 
• 501-53-1 benzyl chloroformate 
• 2899-37-8 (S)-methioninol 
• 121421-45-2 N^α-benzyloxycarbonyl-L-methioninol 
• 1152-62-1 Cbz-Met-OH 

Downstream Products

• 137764-57-9 (4S,5R,4'S,5'R)-4,4'-Bis-(2-methylsulfanyl-ethyl)-3,3'-bis-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-[5,5']bioxazolidinyl-2,2'-dione 
• 137649-83-3 (4S,5R,4'S,5'R)-4,4'-Bis-(2-methylsulfanyl-ethyl)-3,3'-bis-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-[5,5']bioxazolidinyl-2,2'-dione 
• 137649-71-9 (3S,4R,5R,6S)-3,6-Bis-1,8-bis(methylthio)-4,5-octanediol 
• 121421-45-2 N^α-benzyloxycarbonyl-L-methioninol 

Relevant articles and documents

α-Amino Aldehydes as Readily Available Chiral Aldehydes for Rh-Catalyzed Alkyne Hydroacylation

Readily available α-amino aldehydes, incorporating a methylthiomethyl (MTM) protecting group on nitrogen, are shown to be efficient substrates in Rh-catalyzed alkyne hydroacylation reactions. The reactions are performed under mild conditions, employing a small-bite-angle bis-phosphine ligand, allowing for good functional group tolerance with high stereospecificity. Amino aldehydes derived from glycine, alanine, valine, leucine, phenylalanine, isoleucine, serine, tryptophan, methionine, and cysteine were successfully employed, as was an enantiomerically enriched α-OMTM-aldehyde derived from phenyllactic acid. The synthetic utility of the α-amino enone products is demonstrated in a short enantioselective synthesis of the natural product sphingosine.

Pinacol Homocoupling of (S)-2- Aldehydes by 2. Synthesis of C2-Symmetric (1S,2R,3R,4S)-1,4-Diamino 2,3-Diols

Six (S)-2- aldehydes 3a-f were homocoupled by 2 (1) to give C2-symmetric (1S,2R,3R,4S)-1,4-bis 2,3-diols 4a-f in good yield.High-yield conversions of the diols to biso

A new method to synthesize α aminoaldehydes

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