137654-21-8 Usage
Description
2-Fluoro-6-methoxybenzoic acid is a white crystalline powder that serves as a key starting material in the synthesis of various organic compounds, particularly in the pharmaceutical industry. Its unique chemical structure, featuring a fluorine atom and a methoxy group, provides distinct properties that make it valuable for specific applications.
Uses
Used in Pharmaceutical Industry:
2-Fluoro-6-methoxybenzoic acid is used as a starting material for the synthesis of dihydro-0-methylsterigmatocystin, a natural mycotoxin. 2-FLUORO-6-METHOXYBENZOIC ACID has potential applications in the development of new drugs and therapeutic agents, particularly in the area of cancer research.
Used in Organic Synthesis:
2-Fluoro-6-methoxybenzoic acid is used as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique chemical properties allow for the creation of novel molecules with potential applications in different industries.
Used in Research and Development:
Due to its unique structure and reactivity, 2-fluoro-6-methoxybenzoic acid is utilized in research and development laboratories for the exploration of new chemical reactions and the synthesis of novel compounds. This contributes to the advancement of scientific knowledge and the discovery of new materials with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 137654-21-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,6,5 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 137654-21:
(8*1)+(7*3)+(6*7)+(5*6)+(4*5)+(3*4)+(2*2)+(1*1)=138
138 % 10 = 8
So 137654-21-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FO3/c1-12-6-4-2-3-5(9)7(6)8(10)11/h2-4H,1H3,(H,10,11)
137654-21-8Relevant articles and documents
Total synthesis of the ansamycin antibiotic (+)-thiazinotrienomycin E
Smith III, Amos B.,Wan, Zehong
, p. 3738 - 3753 (2007/10/03)
The first total synthesis of (+)-thiazinotrienomycin E (1), member of a novel class of cytotoxic ansamycin antibiotics, has been achieved. Key features of the synthetic strategy include (a) the efficient construction of sulfone 7 incorporating TBS protection of the aniline, (b) an improved synthesis of allyl chloride (-)-6, the advanced intermediate employed in our trienomycins A and F total syntheses, (c) application of the Kocienski modified Julia protocol to elaborate the E,E,E-triene subunit in a stereo- controlled fashion, (d) an efficient union of sulfone 7 with advanced iodide 62, and (e) Mukaiyama macrolactamization to access the thiazinotrienomycin macrocyclic ring.
A Complex Induced Proximity Effect in the Anionic Fries Rearrangement of o-Iodophenyl Benzoates: Synthesis of Dihydro-O-methylsterigmatocystin and Other Xanthones
Horne, Stephen,Rodrigo, Russell
, p. 4520 - 4522 (2007/10/02)
The success of an anionic Fries rearrangement, used to synthesise dihydro-O-methylsterigmatocystin and other xanthones, is dependent on the presence of a remote methoxyl substituent.
