137678-86-5

Basic information

• Product Name: 2(1H)-Pyridinone,6-acetyl-
• Synonyms: 2(1H)-Pyridinone,6-acetyl-;2(1H)-Pyridinone, 6-acetyl- (9CI);6-acetyl-2(1H)-Pyridinone
• CAS NO: 137678-86-5
• Molecular Formula: C7H7NO2
• Molecular Weight: 137.13598
• Product Categories: PYRIDINE;ACETYLGROUP
• Mol File: 137678-86-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 398.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.194±0.06 g/cm3(Predicted)
• PKA: 9.03±0.10(Predicted)
• CAS DataBase Reference: 2(1H)-Pyridinone,6-acetyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyridinone,6-acetyl-(137678-86-5)
• EPA Substance Registry System: 2(1H)-Pyridinone,6-acetyl-(137678-86-5)

Safety Data

• Hazardous Substances Data: 137678-86-5(Hazardous Substances Data)

Usage

Appearance

White to light yellow solid This chemical compound is a solid with a pale color that ranges from white to light yellow.

Molecular weight

149.15 g/mol The molecular weight of 2(1H)-Pyridinone,6-acetylis 149.15 grams per mole, which is a measure of its relative mass.

Building block in synthesis

Pharmaceuticals, agrochemicals, and other organic compounds 2(1H)-Pyridinone,6-acetylis commonly used as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other organic compounds.

Medical applications

Drugs for neurological disorders, pain management, and cancer treatment This chemical compound is used in the production of drugs for a variety of medical conditions, including neurological disorders, pain management, and cancer treatment.

Anti-inflammatory and antioxidant properties

2(1H)-Pyridinone,6-acetylhas been studied for its potential anti-inflammatory and antioxidant properties, which could make it a valuable compound in the field of medicinal chemistry.

Upstream product

• 21190-93-2 1-(6-methoxypyridin-2-yl)ethan-1-one 

Relevant articles and documents

Divergent Solution and Solid-State Structures of Mono- And Dinuclear Nickel(II) Pyridone Complexes

The chelating 2-pyridone ligand (E)-6-(1-((2-(methylthio)phenyl)imino)ethyl)pyridin-2(1H)-one (1) has been used to synthesize five nickel(II) complexes that have been characterized by single-crystal X-ray diffraction, UV/vis and IR spectroscopies, and benchtop magnetometry. Reaction of NiX2 (X = BF4, Cl) with 1 yielded the C2-symmetric halide-bridged Ni dimers [(μ-F)Ni2(κN,N,O-1-)2(κN,N-1)2](BF4) (2) and [(μ-Cl)Ni2(κN,N,O-1-)2(κN,N-1-)(κN,N-1)] (3), where 2 is formed via a rare example of fluoride abstraction from BF4 - by a transition metal. Remarkably, the reaction of Ni(OAc)2 with 1 followed by different methods of crystallization yielded three different products: the dimer [(μ-OH2)Ni2(κN,N,O-1-)(κN,N-1-)(κN,N-1)(OAc)2] (4), as well as the monomers [Ni(κN,N-1-)2(MeOH)2] (5) and [Ni(κN,N-1-)(κN,N-1)(OAc)(OH2)] (6). This observation is emblematic of the soft energy landscape of coordination motifs and nuclearity that pyridone ligands provide with late 3d transition metals. To better understand the solution versus solid-state speciation, solid-state UV/vis reflectance and solution-state UV/vis absorbance spectra were obtained. Surprisingly, the solution-state UV/vis spectra of 4 and 6 each provided nearly identical absorption spectra (λmax ≈ 360 nm), which matched neither of the solid-state reflectance spectra of 4 or 6 (λ ≈ 590, 790, 970 nm; 3A2g → 3T1g 3A2g →1E2g, and 3A2g → 3T2g, respectively). Rather, the solution spectra are consistent only with the spectroscopic features (MLCT) of a conventional square-planar Ni(II) species.