137684-19-6

Basic information

• Product Name: Benzeneacetaldehyde, 2-fluoro-alpha-oxo- (9CI)
• Synonyms: Benzeneacetaldehyde, 2-fluoro-alpha-oxo- (9CI)
• CAS NO: 137684-19-6
• Molecular Formula: C₈H₅FO₂
• Molecular Weight: 152.1225032
• Product Categories: HALIDE
• Mol File: 137684-19-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 212.8±32.0 °C(Predicted)
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzeneacetaldehyde, 2-fluoro-alpha-oxo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, 2-fluoro-alpha-oxo- (9CI)(137684-19-6)
• EPA Substance Registry System: Benzeneacetaldehyde, 2-fluoro-alpha-oxo- (9CI)(137684-19-6)

Safety Data

• Hazardous Substances Data: 137684-19-6(Hazardous Substances Data)

Upstream product

• 445-27-2 2'-Fluoroacetophenone 
• 104-15-4 toluene-4-sulfonic acid 
• 766-49-4 (2-fluorophenyl)acetylene 

Downstream Products

• 160014-08-4 1-(2-Fluoro-benzoyl)-9-methoxymethyl-9H-β-carboline-3-carboxylic acid ethyl ester 
• 935479-79-1 2,2-bis-benzyloxy-1-(2-fluoro-phenyl)-ethanone 
• 1360871-34-6 3-(4-bromophenyl)-4-(2-fluorophenyl)-7-methoxyimidazo[1,5-a]quinoxaline 
• 1373435-96-1 C₂₃H₁₈FNO₃S 
• 1373436-09-9 C₁₆H₁₄FNO 
• 1373435-97-2 C₂₅H₂₀FNO₅S 
• 1373436-10-2 C₁₈H₁₆FNO₃ 
• 1286754-91-3 2-(2-fluorophenyl)pyrazine 
• 573701-88-9 methyl (±)-2-amino-2-(2-fluorophenyl)acetate 
• 132115-73-2 methyl 2-fluoro-α-oxo-benzeneacetate 

Relevant articles and documents

Synthesis of π-Extended Heterocycles via Rh(III)-Catalyzed Oxidative Annulation of 5-Aryl Pyrazinones with Alkynes

The Rh(III)-catalyzed C-H functionalization and subsequent oxidative annulation between 5-aryl pyrazinones and internal alkynes are reported. This protocol provides facile access to a wide range of pyrazinone-linked naphthalenes via the C(sp2)-H alkenylat

Nature of the Nucleophilic Oxygenation Reagent Is Key to Acid-Free Gold-Catalyzed Conversion of Terminal and Internal Alkynes to 1,2-Dicarbonyls

2,3-Dichloropyridine N-oxide, a novel oxygen transfer reagent, allows the conductance of the gold(I)-catalyzed oxidation of alkynes to 1,2-dicarbonyls in the absence of any acid additives and under mild conditions to furnish the target species, including those derivatized by highly acid-sensitive groups. The developed strategy is effective for a wide range of alkyne substrates such as terminal- and internal alkynes, ynamides, alkynyl ethers/thioethers, and even unsubstituted acetylene (40 examples; yields up to 99%). The oxidation was successfully integrated into the trapping of reactive dicarbonyls by one-pot heterocyclization and into the synthesis of six-membered azaheterocycles. This synthetic acid-free route was also successfully applied for the total synthesis of a natural 1,2-diketone.

Enantioselective Cyanosilylation of α,α-Dialkoxy Ketones by Using Phosphine-Thiourea Dual-Reagent Catalysis

The first highly enantioselective cyanosilylation of α,α-dialkoxy ketones enabled by a dual-reagent catalysis has been developed. With the combination of a chiral bifunctional phosphine-thiourea and methyl acrylate, the key organophosphorus zwitterion intermediate was generated in situ as a novel Lewis base, which catalyzed the enantioselective cyanosilylation reaction in excellent yields (up to 99 %) with good-to-excellent enantioselectivities (up to 94 % ee).