1377321-96-4Relevant articles and documents
Stereocontrolled synthesis of bicyclic ureas and sulfamides via Pd-catalyzed alkene carboamination reactions
Babij, Nicholas R.,Boothe, Jordan R.,McKenna, Grace M.,Fornwald, Ryan M.,Wolfe, John P.
, p. 4228 - 4243 (2019/05/04)
The synthesis of bicyclic ureas and sulfamides via palladium-catalyzed alkene carboamination reactions between aryl/alkenyl halides/triflates and alkenes bearing pendant cyclic sulfamides and ureas is described. The substrates for these reactions are gene
Asymmetric total synthesis of (+)-merobatzelladine B
Babij, Nicholas R.,Wolfe, John P.
supporting information; experimental part, p. 4128 - 4130 (2012/06/04)
Putting the syn in synthesis: The first total synthesis of (+)-merobatzelladineB was accomplished using an iterative sequence of stereoselective palladium-catalyzed alkene carboamination reactions for formation of two of the three rings. This represents a new strategy for the generation of polycyclic guanidine natural products, and provides access to compounds with a synrelationship between the C6 hydrogen atom and the C8 alkyl group. Copyright
