1378284-25-3

Basic information

• Product Name: methyl 4-[(2-bromo-5-methoxyphenyl)ethynyl]benzoate
• Synonyms: methyl 4-[(2-bromo-5-methoxyphenyl)ethynyl]benzoate
• CAS NO: 1378284-25-3
• Molecular Weight: 345.192
• Mol File: 1378284-25-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 4-[(2-bromo-5-methoxyphenyl)ethynyl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-[(2-bromo-5-methoxyphenyl)ethynyl]benzoate(1378284-25-3)
• EPA Substance Registry System: methyl 4-[(2-bromo-5-methoxyphenyl)ethynyl]benzoate(1378284-25-3)

Safety Data

• Hazardous Substances Data: 1378284-25-3(Hazardous Substances Data)

Upstream product

• 4897-68-1 2-iodo-4-methoxybromobenzene 
• 3034-86-4 4-ethynylbenzoic acid methyl ester 

Downstream Products

• 1378284-26-4 methyl 4-[[5-methoxy-2-[(trimethylsilyl)ethynyl]phenyl]-ethynyl]benzoate 

Relevant articles and documents

Gold(I)-catalyzed regioselective inter-/intramolecular addition cascade of di- and triynes for direct construction of substituted naphthalenes

The gold-catalyzed cascade intermolecular addition-intramolecular carbocyclization reaction of dialkynylbenzenes was developed. In this reaction, regioselective addition of an external nucleophile toward the terminal alkyne and subsequent 6-endo-dig cyclization proceeded to give the 1,3-disubstituted naphthalenes in good yields. The direct synthesis of disubstituted chrysenes via a gold-catalyzed addition and double cyclization cascade using a triyne-type substrate was also achieved.