137858-24-3

Basic information

• Product Name: Piperazine, 1-acetyl-4-[5-(cyclopropylamino)-2-fluoro-4-nitrophenyl]-
• CAS NO: 137858-24-3
• Molecular Formula: C15H19FN4O3
• Molecular Weight: 322.339
• Mol File: 137858-24-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-acetyl-4-[5-(cyclopropylamino)-2-fluoro-4-nitrophenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-acetyl-4-[5-(cyclopropylamino)-2-fluoro-4-nitrophenyl]-(137858-24-3)
• EPA Substance Registry System: Piperazine, 1-acetyl-4-[5-(cyclopropylamino)-2-fluoro-4-nitrophenyl]-(137858-24-3)

Safety Data

• Hazardous Substances Data: 137858-24-3(Hazardous Substances Data)

Upstream product

• 13889-98-0 N-acetylpiperidine 
• 135861-04-0 5-chloro-n-cyclopropyl-4-fluoro-2-nitroaniline 
• 578-28-9 1-Chloro-2,5-difluoro-4-nitrobenzene 

Downstream Products

• 137858-25-4 tert-butyl 4-<5-cyclopropylamino)-2-fluoro-4-nitrophenyl>-1-piperazinecarboxylate 
• 137858-17-4 5-cyclopropyl-8-fluoro-7-(1-piperazinyl)pyrimido<1,6-a>benzimidazole-1,3(2H,5H)-dione trifluoroacetate 
• 137858-18-5 5-cyclopropyl-8-fluoro-2-hydroxy-7-(1-piperazinyl)-pyrimido[1,6-a]benzimidazole-1,3(2H,5H)-dione hydrochloride 
• 137858-31-2 tert-butyl 4-[2-(benzyloxy)-5-cyclopropyl-8-fluoro-1,2,3,5-tetrahydro-1,3-dioxopyrimido[1,6-a]benzimidazol-7-yl]-1-piperazinecarboxylate 
• 137858-30-1 tert-butyl 4-<2-<<(benzyloxycarbonyl)carbamoyl>methyl>-1-cyclopropyl-5-fluoro-6-benzimidazolyl>-1-piperazinecarboxylate 
• 139495-73-1 tert-butyl 4-<5-cyclopropylamino)-2-fluoro-4-aminophenyl>-1-piperazinecarboxylate 
• 135861-05-1 4-<5-cyclopropylamino)-2-fluoro-4-nitrophenyl>piperazine 

Relevant articles and documents

Amino substituted pyrimido[1,6-2]benzimidazoles

The present invention relates to novel substituted pyrimidobenzimidazole derivatives of the formula STR1 wherein the substituents are as described in the specification, and pharmaceutically acceptable salts thereof. The products have an inhibitory action

Procedure for the preparation of N-cyclopropyl-4-fluoroanilines

Procedure for the preparation of N-cyclopropyl-4-fluoroanilines of formula I. By selective reaction of II with cyclopropylamine, piperazines or pyrrolidines, III is obtained. Its acetylation and reduction yields IV which by de-amination leads to I. R1 is