137860-00-5

Basic information

• Product Name: Benzenepropanoic acid, 4-nitro-a-(1-oxobutyl)-, ethyl ester
• CAS NO: 137860-00-5
• Molecular Formula: C15H19NO5
• Molecular Weight: 293.32
• Mol File: 137860-00-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, 4-nitro-a-(1-oxobutyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 4-nitro-a-(1-oxobutyl)-, ethyl ester(137860-00-5)
• EPA Substance Registry System: Benzenepropanoic acid, 4-nitro-a-(1-oxobutyl)-, ethyl ester(137860-00-5)

Safety Data

• Hazardous Substances Data: 137860-00-5(Hazardous Substances Data)

Upstream product

• 3249-68-1 ethyl butyroyl acetate 
• 100-11-8 1-bromomethyl-4-nitro-benzene 

Downstream Products

• 137860-07-2 4-(4-Nitro-benzyl)-5-propyl-2-(2,2,2-trifluoro-ethyl)-2H-pyrazol-3-ol 
• 137861-22-4 2-<<4-<<5-<(ethoxycarbonylmethyl)oxy>-1-methyl-3-n-propylpyrazol-4-yl>methyl>phenyl>aminocarbonyl>benzenesulfonic acid 
• 137860-18-5 [5-Ethoxycarbonylmethoxy-4-(4-nitro-benzyl)-3-propyl-pyrazol-1-yl]-acetic acid ethyl ester 
• 137860-14-1 [4-(4-Nitro-benzyl)-5-propyl-2-(2,2,2-trifluoro-ethyl)-2H-pyrazol-3-yloxy]-acetic acid methyl ester 
• 137861-24-6 [4-(4-Amino-benzyl)-5-ethoxycarbonylmethoxy-3-propyl-pyrazol-1-yl]-acetic acid ethyl ester 
• 137860-24-3 2-[4-(4-Nitro-benzyl)-5-propyl-2-(2,2,2-trifluoro-ethyl)-2H-pyrazol-3-yloxy]-ethanol 
• 137861-00-8 [4-(4-Amino-benzyl)-5-propyl-2-(2,2,2-trifluoro-ethyl)-2H-pyrazol-3-yloxy]-acetic acid methyl ester 
• 137860-10-7 ethyl 2-<1-methyl-4-(4-nitrobenzyl)-3-n-propylpyrazol-5-yl>oxyacetate 

Relevant articles and documents

Synthesis and angiotensin II receptor antagonist activity of C-linked pyrazole derivatives

The synthesis and pharmacological activity of new nonpeptide angiotensin II (AII) receptor antagonists are presented. These 5-O-substituted and 5-C-substituted 3-alkylpyrazole derivatives represent a new series of antagonists and have led to the discovery

TRIAZOLOPYRIMIDINE DERIVATIVES WHICH ARE ANGIOTENSIN II RECEPTOR ANTAGONISTS

The present invention relates to the derivatives of formula: STR1 and to their tautomeric forms as well as to their addition salts and to their use in therapy, in particular for the treatment of cardiovascular diseases, especially for the treatment of hypertension, cardiac insufficiency and diseases of the arterial wall.