137967-42-1Relevant articles and documents
Stereoselective 1,3-dipolar cycloadditions of nitrones derived from amino acids. Asymmetric synthesis of N-(alkoxycarbonylmethyl)-3-hydroxypyrrolidin-2- ones Dedicated to Professor Giovanni Romeo on occasion of his 70th birthday
Merino, Pedro,Greco, Graziella,Tejero, Tomás,Hurtado-Guerrero, Ramon,Matute, Rosa,Chiacchio, Ugo,Corsaro, Antonino,Pistarà, Venerando,Romeo, Roberto
, p. 9381 - 9390 (2013/10/08)
Diastereoselective asymmetric 1,3-dipolar cycloadditions of N-(alkoxycarbonylmethyl) nitrones derived from glycine, alanine and phenylalanine have been studied both experimentally and theoretically. Asymmetric induction is evaluated by either introducing
PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF
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Page/Page column 89-93, (2008/06/13)
Disclosed is a process for producing an asymmetric mono-substituted alkylated compound of an α-amino acid which is represented by a specific formula by using an aldimine-type Schiff base. In the process, the alkylation of an aldimine-type Schiff base in a medium in the presence of an optically active quaternary ammonium salt phase transfer catalyst and an inorganic base is started, and subsequently the reaction is quenched at any time preceding the completion of the stoichimetrical reaction, thereby yielding a mono-substituted alkylated product having a high optical purity.
The catalysis and asymmetric induction of chiral reverse micelle: Synthesis of optically active α-amino acids
Sun, Peipei,Zhang, Yongmin
, p. 4173 - 4179 (2007/10/03)
Through alkylation of N-benzylideneglycine ethyl ester in chiral reverse micelle, followed by hydrolysis of the resulting products, optically active α-amino acids were synthesized.