13797-62-1

Basic information

• Product Name: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID
• Synonyms: AKOS BBS-00007904;2-(2-METHYL-1,3-THIAZOL-4-YL)ACETIC ACID;(2-METHYL-THIAZOL-4-YL)-ACETIC ACID;(2-METHYL-1,3-THIAZOL-4-YL)ACETIC ACID;CHEMBRDG-BB 4400881;IFLAB-BB F0848-0152;(2-METHYL-THIAZOL-4-YL)-ACETIC【MFCD02669593】;(2-methyl-1,3-thiazol-4-yl)acetic acid(SALTDATA: FREE)
• CAS NO: 13797-62-1
• Molecular Formula: C₆H₇NO₂S
• Molecular Weight: 157.19
• Mol File: 13797-62-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 125-126 °C
• Boiling Point: 304.9 °C at 760 mmHg
• Flash Point: 138.2 °C
• Appearance: /
• Density: 1.356 g/cm³
• Vapor Pressure: 0.000372mmHg at 25°C
• PKA: 4.79±0.10(Predicted)
• CAS DataBase Reference: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID(13797-62-1)
• EPA Substance Registry System: (2-METHYL-THIAZOL-4-YL)-ACETIC ACID(13797-62-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 13797-62-1(Hazardous Substances Data)

Usage

General Description

(2-Methyl-thiazol-4-yl)-acetic acid is a chemical compound that belongs to the thiazole class of organic molecules. It is a derivative of thiazole with a methyl group attached to the second carbon atom. (2-METHYL-THIAZOL-4-YL)-ACETIC ACID is also known as Zomig, which is a medication used for the treatment of migraines. It works by narrowing blood vessels in the brain and reducing the chemicals in the body that can trigger headaches, nausea, and other migraine symptoms. The acetic acid component of this compound is a carboxylic acid, which can act as a weak acid in chemical reactions. Overall, (2-Methyl-thiazol-4-yl)-acetic acid has pharmaceutical and biological properties that make it useful for managing migraines.

InChI:InChI=1/C6H7NO2S/c1-4-7-5(3-10-4)2-6(8)9/h3H,2H2,1H3,(H,8,9)/p-1

Upstream product

• 37128-24-8 ethyl (2-methyl-1,3-thiazol-4-yl)acetate 
• 638-07-3 ethyl (2-chloroaceto)acetate 
• 857982-41-3 thiazole-2,4-diyl-di-acetic acid diethyl ester 

Downstream Products

• 541-58-2 2,4-dimethylthiazole 
• 15719-64-9 methylammonium carbonate 
• 121357-04-8 2-(2-methylthiazol-4-yl)ethanol 
• 1444405-05-3 C₂₃H₂₇N₇O₂S 
• 1277098-56-2 benzyl-2-[(2-methylthiazol-4-yl)methyl]-1H-benzoimidazole-5-carboxylic acid 
• 1277098-54-0 methyl 1-benzyl-2-[(2-methylthiazol-4-yl)methyl]-1H-benzoimidazole-5-carboxylate 
• 408367-58-8 N-(4-{[(2-Methyl-1,3-thiazol-4-yl)acetyl]amino}phenyl)-4'-(trifluoromethyl)-1,1'-biphenyl-2-carboxamide 

Relevant articles and documents

Ramoplanin derivatives possessing antibacterial activity

Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

Diphosphonate derivatives, pharmaceutical compositions and methods of use for calcium disturbances

The present invention produces alkyldiphosphonic acid derivative of the general formula: STR1 wherein Het is a heteroaromatic five-membered ring containing to 3 heteroatoms which can be partly hydrogenated and optionally substituted one or more times by alkyl, alkoxy, phenyl, cyclohexyl, cyclohexylmethyl, halogen or amino, and two adjacent alkyl substituents can together also form a ring, Y is a hydrogen atom or a lower alkyl radical, X is a hydrogen atom, a hydroxyl group or an amino group optionally substituted by lower alkyl and R is a hydrogen atom or a lower alkyl radical, with the proviso that Het is not a pyrazole ring; as well as the pharmacologically acceptable salts thereof. The present invention also provides processes for the prepearation of these compounds and pharmaceutical compositions containing them useful for the treatment or prophylaxis of calcium metabolism disturbances or disease as for example osteoporosis, Bechterew's disease, bone metastases, urolithiasis, heterotropic ossifications, rheumatoid arthritis osteoarthritis or degenerative arthrosis.