1379771-88-6

Basic information

• Product Name: Boc-4-(6-(2-pyrimidinyl)-1,2,4,5-tetrazin-3-yl)benzylamine
• Synonyms: Boc-4-(6-(2-pyrimidinyl)-1,2,4,5-tetrazin-3-yl)benzylamine
• CAS NO: 1379771-88-6
• Molecular Weight: 365.395
• Mol File: 1379771-88-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Boc-4-(6-(2-pyrimidinyl)-1,2,4,5-tetrazin-3-yl)benzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-4-(6-(2-pyrimidinyl)-1,2,4,5-tetrazin-3-yl)benzylamine(1379771-88-6)
• EPA Substance Registry System: Boc-4-(6-(2-pyrimidinyl)-1,2,4,5-tetrazin-3-yl)benzylamine(1379771-88-6)

Safety Data

• Hazardous Substances Data: 1379771-88-6(Hazardous Substances Data)

Upstream product

• 14080-23-0 2-cyanopyrimidine 
• 66389-80-8 tert-butyl N-[(4-cyanophenyl)methyl]carbamate 
• 15996-76-6 4-cyanobenzylamine hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1379771-98-8 N-BodipyTMR-4-(6-(2-pyrimidinyl)-1,2,4,5-tetrazin-3-yl)benzylamine 
• 1379771-90-0 N-biotin-4-(6-(2-pyrimidinyl)-1,2,4,5-tetrazin-3-yl)benzylamine 
• 1345955-30-7 C₁₃H₁₁N₇ 

Relevant articles and documents

Fast and pH-Independent Elimination of trans-Cyclooctene by Using Aminoethyl-Functionalized Tetrazines

The inverse-electron-demand Diels–Alder/pyridazine elimination tandem reaction, in which the allylic substituent on trans-cyclooctene is eliminated following reaction with tetrazines, is gaining interest as a versatile bioorthogonal process. One potential shortcoming of such currently used reactions is their propensity to proceed faster and more efficiently at lower pH, a feature caused by the nature of the tetrazines used. Here, we present aminoethyl-substituted tetrazines as the first pH-independent reagents showing invariably fast elimination kinetics at all biologically relevant pH values.