1380213-66-0Relevant articles and documents
A concise and versatile double-cyclization strategy for the highly stereoselective synthesis and arylative dimerization of aspidosperma alkaloids
Medley, Jonathan William,Movassaghi, Mohammad
, p. 4572 - 4576 (2012/07/03)
Building cycles: A strategy for the concise, stereoselective synthesis of aspidosperma alkaloids and related structures via a common putative diiminium ion intermediate is reported. The approach enables the dimerization of aspidosperma-type structures at the sterically hindered C2 position. The intermediate is prepared in one step from the shown lactam through an electrophilic double-cyclization cascade (see scheme; Tf= trifluoromethanesulfonyl). Copyright