1380520-62-6Relevant articles and documents
A simple metal-free synthesis of 2-substituted pyridine-4,5-dicarboxylates and their N-oxides
Bezen?ek, Jure,Prek, Benjamin,Gro?elj, Uro?,Kasuni?, Marta,Svete, Jurij,Stanovnik, Branko
experimental part, p. 4719 - 4731 (2012/07/28)
Herein a simple, metal-free synthesis of 2-alkyl-, 2-cycloalkyl-, 2-aryl-, and 2-heteroaryl-substituted pyridine 3,4-dicarboxylates and their N-oxides from the corresponding methyl ketones in good to excellent yield, demonstrated with 22 examples in each case, is described. The method complements the current coupling reactions of 2-heterocyclic organometallic reagents.