1380544-53-5Relevant articles and documents
Gold-catalyzed intramolecular hydroalkoxylation/cyclization of conjugated dienyl alcohols
Chandrasekhar,Ryu, Jae-Sang
, p. 4805 - 4812 (2012/08/08)
Catalytic intramolecular additions of hydroxyl groups to tethered conjugated dienes are described. The reactions proceed smoothly at 60 °C in the presence of 5 mol % of (PPh3)AuCl/AgOTf as a catalyst. A broad range of structurally diverse conjugated dienes produce substituted tetrahydrofurans and tetrahydropyrans in good yields. This reaction represents an atom-economic route to construct five- and six-membered cyclic ethers.