13807-17-5Relevant articles and documents
Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
Lin, Ronghui,Johnson, Sigmond G.,Connolly, Peter J.,Wetter, Steven K.,Binnun, Eva,Hughes, Terry V.,Murray, William V.,Pandey, Niranjan B.,Moreno-Mazza, Sandra J.,Adams, Mary,Fuentes-Pesquera, Angel R.,Middleton, Steven A.
scheme or table, p. 2333 - 2337 (2009/12/07)
2,7-Diamino-thiazolo[4,5-d]pyrimidine analogues were synthesized as novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. Representative compounds showed potent and selective EGFR inhibitory activities and inhibited in vitro cellular p
Use of 2,4-diaminothiazole derivatives
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, (2008/06/13)
2,4-Diaminothiazole derivatives which inhibit GSK-3 (glycogen synthase kinase-3) and which are useful for the treatment and/or prevention disorders and diseases wherein an inhibition of GSK-3 is beneficial, especially especially Alzheimer's disease, bipolar disorder, IGT (impaired glucose tolerance), Type 1 diabetes, Type 2 diabetes and obesity.