138071-82-6

Basic information

• Product Name: Gadobutrol
• Synonyms: Gadobutrol;GadoliniuM,[10-[2,3-dihydroxy-1-(hydroxyMethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-;gallium 10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate;CL124;gadolinium(III) 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
• CAS NO: 138071-82-6
• Molecular Formula: C18H31N4O9.Gd
• Molecular Weight: 604.712
• EINECS: 1308068-626-2
• Product Categories: API
• Mol File: 138071-82-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 738.5°Cat760mmHg
• Flash Point: 400.4°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 3.59E-25mmHg at 25°C
• Storage Temp.: Refrigerator
• Solubility: Water (Slightly)
• CAS DataBase Reference: Gadobutrol(CAS DataBase Reference)
• NIST Chemistry Reference: Gadobutrol(138071-82-6)
• EPA Substance Registry System: Gadobutrol(138071-82-6)

Safety Data

• Hazardous Substances Data: 138071-82-6(Hazardous Substances Data)

Usage

Description

Gadobutrol is a gadolinium-based MRI contrast agent (GBCA) that enhances the visualization of internal body structures during magnetic resonance imaging (MRI) scans. It is designed to improve the clarity and detail of the images, allowing for more accurate diagnoses and assessments of various medical conditions.

Uses

Used in Medical Imaging:
Gadobutrol is used as an MRI contrast agent for improving the image quality and diagnostic accuracy of MRI scans. It helps in visualizing the brain and other internal body structures more clearly, which is particularly useful for detecting and diagnosing various medical conditions, such as tumors, inflammation, and vascular disorders.
Used in Diagnostic Procedures:
Gadobutrol injection is used in diagnostic procedures to provide a clearer picture of the body's internal structures during an MRI scan. This enhanced visualization assists doctors in making more informed decisions about the patient's condition and the appropriate course of treatment.

Mechanism of action

In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease.

Waste Disposal

Expired or waste pharmaceuticals shall carefully take into consideration applicable DEA, EPA, and FDA regulations. It is not appropriate to dispose by flushing the pharmaceutical down the toilet or discarding to trash. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

InChI:InChI=1/C18H34N4O9.Ga/c23-12-14(15(25)13-24)22-7-5-20(10-17(28)29)3-1-19(9-16(26)27)2-4-21(6-8-22)11-18(30)31;/h14-15,23-25H,1-13H2,(H,26,27)(H,28,29)(H,30,31);/q;+3/p-3/t14-,15-;/m1./s1

Related news

Gadobutrol (cas 138071-82-6) enhances T1-weighted MRI of nerve cells08/16/2019

Three-dimensional T1-weighted MRI of mouse brain in vivo (9.4 T, 80 μm isotropic resolution) identified assemblies of nerve cell bodies in the habenula, hippocampal formation, locus coeruleus, dorsal motor nucleus of vagus, and nucleus ambiguus as high signal intensities, while suppressing the ...detailed