138113-07-2 Usage
Description
2-(7-Methoxynaphthalen-1-yl)acetamide is an organic compound characterized by its naphthalene-based structure and amide functional group. It is a derivative of naphthalene with a methoxy group at the 7th position and an acetamide group at the 2nd position. 2-(7-Methoxynaphthalen-1-yl)acetamide is known for its potential applications in the pharmaceutical and chemical industries due to its unique structural features and interactions with biological targets.
Uses
Used in Pharmaceutical Industry:
2-(7-Methoxynaphthalen-1-yl)acetamide is used as a key intermediate in the synthesis of various melatonin analogs, such as Agomelatine Impurity 6. These analogs contain a naphthalene moiety instead of the traditional indole nucleus and exhibit high affinity for the melatonin receptor. The compound plays a crucial role in the development of novel therapeutic agents targeting melatonin receptors, which can be beneficial for treating various sleep disorders, mood disorders, and other conditions related to the circadian rhythm.
Used in Chemical Synthesis:
In the chemical industry, 2-(7-Methoxynaphthalen-1-yl)acetamide can be utilized as a building block for the synthesis of a wide range of naphthalene-based compounds with diverse applications. These applications may include the development of new materials, dyes, pigments, and other specialty chemicals that can be used in various industrial processes. The compound's unique structural features make it a valuable starting material for the creation of novel chemical entities with potential commercial and technological significance.
Check Digit Verification of cas no
The CAS Registry Mumber 138113-07-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,1,1 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 138113-07:
(8*1)+(7*3)+(6*8)+(5*1)+(4*1)+(3*3)+(2*0)+(1*7)=102
102 % 10 = 2
So 138113-07-2 is a valid CAS Registry Number.
InChI:InChI=1S/C13H13NO2/c1-16-11-6-5-9-3-2-4-10(7-13(14)15)12(9)8-11/h2-6,8H,7H2,1H3,(H2,14,15)
138113-07-2Relevant articles and documents
Synthesis of the naphthalenic bioisostere of indorenate
Yous,Depreux,Renard
, p. 119 - 120 (1993)
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PROCESS FOR THE SYNTHESIS OF AGOMELATINE
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Paragraph 0159; 0160; 0161, (2017/04/04)
Process for the industrial synthesis of the compound of formula (I):
PROCESS FOR PREPARATION OF AGOMELATINE AND CRYSTALLINE FORM I THEREOF
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Page/Page column 16, (2014/01/17)
An improved process for the preparation of agomelatine of formula (I) and a new process for the preparation of crystalline form I of agomelatine are provided.
