138116-34-4 Usage
Description
(4-AMINO-PYRIDIN-3-YL)-METHANOL, also known as 4-Amino-3-pyridinemethanol, is an organic compound that serves as an intermediate in the synthesis of various organic chemicals. It is characterized by its white to light yellow powdery appearance and plays a crucial role in the production of different chemical compounds.
Uses
Used in Chemical Synthesis:
(4-AMINO-PYRIDIN-3-YL)-METHANOL is used as an organic chemical synthesis intermediate for the production of various chemical compounds. Its unique structure allows it to be a versatile building block in the creation of a wide range of molecules with diverse applications across different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4-AMINO-PYRIDIN-3-YL)-METHANOL is used as a key intermediate in the synthesis of drugs with potential therapeutic applications. Its ability to form various molecular structures makes it a valuable component in the development of new medications.
Used in Research and Development:
(4-AMINO-PYRIDIN-3-YL)-METHANOL is also utilized in research and development laboratories for the exploration of new chemical reactions and the synthesis of novel compounds. Its versatility as a chemical intermediate enables scientists to investigate its potential in creating new materials and substances with unique properties.
Used in Material Science:
In the field of material science, (4-AMINO-PYRIDIN-3-YL)-METHANOL can be employed as a component in the development of advanced materials with specific properties. Its role as a chemical intermediate allows for the creation of materials with tailored characteristics, such as improved strength, conductivity, or chemical resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 138116-34-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,1,1 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 138116-34:
(8*1)+(7*3)+(6*8)+(5*1)+(4*1)+(3*6)+(2*3)+(1*4)=114
114 % 10 = 4
So 138116-34-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O/c7-6-1-2-8-3-5(6)4-9/h1-3,9H,4H2,(H2,7,8)
138116-34-4Relevant articles and documents
SUBSTITUTED HETEROCYCLIC AZA DERIVATIVES
-
, (2013/03/26)
The invention relates to heterocyclic aza derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors
Thomas, Allen A.,Le Huerou,De Meese,Gunawardana, Indrani,Kaplan, Tomas,Romoff, Todd T.,Gonzales, Stephen S.,Condroski, Kevin,Boyd, Steven A.,Ballard, Josh,Bernat, Bryan,DeWolf, Walter,Han, May,Lee, Patrice,Lemieux, Christine,Pedersen, Robin,Pheneger, Jed,Poch, Greg,Smith, Darin,Sullivan, Francis,Weiler, Solly,Wright, S. Kirk,Lin, Jie,Brandhuber, Barb,Vigers, Guy
, p. 2206 - 2210 (2008/12/20)
Tumor cells extensively utilize the pentose phosphate pathway for the synthesis of ribose. Transketolase is a key enzyme in this pathway and has been suggested as a target for inhibition in the treatment of cancer. In a pharmacodynamic study, nude mice with xenografted HCT-116 tumors were dosed with 1 ('N3′-pyridyl thiamine'; 3-(6-methyl-2-amino-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium chloride hydrochloride), an analog of thiamine, the co-factor of transketolase. Transketolase activity was almost completely suppressed in blood, spleen, and tumor cells, but there was little effect on the activity of the other thiamine-utilizing enzymes α-ketoglutarate dehydrogenase or glucose-6-phosphate dehydrogenase. Synthesis and SAR of transketolase inhibitors is described.
