1381776-08-4

Basic information

• Product Name: C₁₅H₁₉N₃
• Synonyms: C₁₅H₁₉N₃
• CAS NO: 1381776-08-4
• Molecular Weight: 241.336
• Mol File: 1381776-08-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₉N₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₉N₃(1381776-08-4)
• EPA Substance Registry System: C₁₅H₁₉N₃(1381776-08-4)

Safety Data

• Hazardous Substances Data: 1381776-08-4(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 84539-35-5 (3-bromopyridin-4-yl)-dimethyl-amine 

Relevant articles and documents

Efficient C-3 functionalization of 4-dimethylaminopyridine (DMAP). A straightforward access to new chiral nucleophilic catalysts

Herein, the straightforward C-3 functionalization of 4- dimethylaminopyridine (DMAP) backbone is disclosed. An efficient halogen-metal exchange procedure from 3-bromo DMAP 1 is reported providing a large panel of C-3 functionalized DMAPs. In addition, a Pd-catalysed C-N cross-coupling reaction is also described furnishing new 3-amino DMAPs. These new functionalization pathways led to the resolution-free synthesis of three new chiral DMAP catalysts in few steps and a good overall yield. These new catalysts were evaluated into the Steglich rearrangement giving modest enantioselectivities (up to 20% ee).